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AQP11 Knockout Cell Lines

Gene: AQP11

Official Full Name: aquaporin 11provided by HGNC

Gene Summary: Enables glycerol channel activity; hydrogen peroxide channel activity; and water channel activity. Involved in several processes, including glycerol transmembrane transport; hydrogen peroxide transmembrane transport; and intracellular water homeostasis. Located in cell surface; endoplasmic reticulum; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO19742 AQP11 Knockout cell line (HeLa) Human AQP11 1:3~1:6 Negative Online Inquiry
KO19743 AQP11 Knockout cell line (HCT 116) Human AQP11 1:2~1:4 Negative Online Inquiry
KO19744 AQP11 Knockout cell line (HEK293) Human AQP11 1:3~1:6 Negative Online Inquiry
KO19745 AQP11 Knockout cell line (A549) Human AQP11 1:3~1:4 Negative Online Inquiry

Background

AQP11 Gene Knockout Cell Lines represent a cutting-edge advancement in the field of molecular biology and genetics. These genetically engineered cell lines are designed to have specific deletions in the AQP11 gene, which encodes for aquaporin 11, a member of the water channel protein family. This functionality is critical for understanding cellular osmoregulation, particularly in the context of kidney and brain health.

The primary function of these knockout cell lines is to provide researchers with a robust model to investigate the role of AQP11 in various physiological and pathological processes. By observing the cellular responses in the absence of this water channel, scientists can elucidate mechanisms of fluid transport, cell signaling, and metabolic acidosis. Moreover, these models are invaluable for studying the implications of AQP11 dysregulation in diseases such as polycystic kidney disease or neurological conditions.

The scientific importance of AQP11 Gene Knockout Cell Lines cannot be overstated. They are essential tools for basic and applied research, facilitating advances in drug discovery and therapeutic interventions aimed at correcting aberrant aquaporin function. In clinical settings, understanding the role of AQP11 can lead to targeted treatments for kidney disorders and other water balance-related ailments.

One of the unique selling points of our AQP11 Gene Knockout Cell Lines is their high specificity and reliability. Unlike alternative models, which may offer inconsistent results due to off-target effects, our knockout lines guarantee precise gene editing outcomes, providing a clear pathway for experimentation. Additionally, researchers benefit from a user-friendly protocol conducive to quick implementation in their studies.

The value of AQP11 Gene Knockout Cell Lines is evident in their ability to accelerate the research process by providing clear and interpretable data on aquaporin function. They empower researchers and clinicians to bridge the gap between molecular biology and clinical applications, ultimately contributing to improved health outcomes.

Our company is dedicated to advancing scientific research through high-quality biological products, underpinned by our extensive expertise in genetic engineering and cell line development. By continuously innovating and providing reliable tools like AQP11 Gene Knockout Cell Lines, we strive to support the global research community in achieving groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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