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APPBP2 Knockout Cell Lines

Gene: APPBP2

Official Full Name: amyloid beta precursor protein binding protein 2provided by HGNC

Gene Summary: The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. The encoded protein may be involved in regulating cell death. This gene has been found to be highly expressed in breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO31772 APPBP2 Knockout cell line (HeLa) Human APPBP2 1:3~1:6 Negative Online Inquiry
KO31773 APPBP2 Knockout cell line (HCT 116) Human APPBP2 1:2~1:4 Negative Online Inquiry
KO31774 APPBP2 Knockout cell line (HEK293) Human APPBP2 1:3~1:6 Negative Online Inquiry
KO31775 APPBP2 Knockout cell line (A549) Human APPBP2 1:3~1:4 Negative Online Inquiry

Background

APPBP2 Gene Knockout Cell Lines are specialized biological products designed for precise studies in gene function and disease modeling through the targeted inactivation of the APPBP2 gene. The APPBP2 gene encodes a protein involved in the regulation of various cellular processes, including cell proliferation, apoptosis, and gene expression. By utilizing CRISPR-Cas9 technology for gene editing, these knockout cell lines allow researchers to explore the consequences of APPBP2 loss and its implications on cellular mechanisms and related pathologies.

Key functions of APPBP2 Gene Knockout Cell Lines hinge on their ability to mimic disease states by disabling specific genetic pathways that the APPBP2 gene influences. This inactivation leads to observable phenotypes that can inform research on neurodegenerative diseases, cancer biology, and developmental disorders. The knockouts offer a robust platform to study the molecular interactions and pathways affected by APPBP2 depletion, providing insights critical for therapeutic development.

In research and clinical settings, these cell lines hold significant scientific importance as they serve as invaluable tools for drug screening, biomarker identification, and mechanistic studies. Their specific use in modeling human diseases presents a clear advantage over traditional models that may not adequately reflect human biology.

The unique selling points of APPBP2 Gene Knockout Cell Lines include their reproducibility, high specificity for the APPBP2 gene, and ready adaptability for various experimental needs. Unlike alternative models, these knockout lines can facilitate faster results in gene editing research with a clearer understanding of the gene's involvement in complex biological systems.

For researchers and clinicians looking to advance their work in genetic and cellular studies, APPBP2 Gene Knockout Cell Lines represent an opportunity to achieve precise, reliable outcomes that can propel discoveries forward. With our company's deep expertise in genetic engineering and a commitment to quality, we are proud to offer these cutting-edge products that enhance the capabilities of scientific inquiry.

Please note that all services are for research use only. Not intended for any clinical use.

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