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APOOL Knockout Cell Lines

Gene: APOOL

Official Full Name: apolipoprotein O likeprovided by HGNC

Gene Summary: This gene encodes a protein which contains an apolipoprotein O superfamily domain. This domain is found on proteins in circulating lipoprotein complexes. [provided by RefSeq, Sep 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25982 APOOL Knockout cell line (HeLa) Human APOOL 1:3~1:6 Negative Online Inquiry
KO25983 APOOL Knockout cell line (HCT 116) Human APOOL 1:2~1:4 Negative Online Inquiry
KO25984 APOOL Knockout cell line (HEK293) Human APOOL 1:3~1:6 Negative Online Inquiry
KO25985 APOOL Knockout cell line (A549) Human APOOL 1:3~1:4 Negative Online Inquiry

Background

APOOL Gene Knockout Cell Lines are advanced biological tools designed to aid researchers in the functional analysis of specific genes through the complete abrogation of their expression. These cell lines are engineered using CRISPR-Cas9 technology, which enables the targeted alteration of genomic sequences, facilitating the creation of knockout models that serve as invaluable resources in understanding gene function, gene interactions, and the underlying mechanisms of various biological processes.

The key function of APOOL Gene Knockout Cell Lines lies in their ability to produce homogeneous populations of cells lacking specific genes. This process provides insights into gene function by allowing researchers to observe phenotypic changes resulting from the absence of the target gene. The precise mechanism involves the introduction of single-guide RNAs (sgRNAs) alongside the Cas9 nuclease, which introduces double-strand breaks at the desired loci, leading to insertions or deletions that effectively disrupt gene function.

The scientific importance of our knockout cell lines is significant, as they can be utilized in a myriad of applications, including drug development, disease modeling, functional genomics, and target validation. In clinical research, they present opportunities to uncover pathogenic mechanisms of diseases and identify potential therapeutic targets, thereby driving forward precision medicine initiatives.

APOOL Gene Knockout Cell Lines distinguish themselves from alternatives through rigorous quality control measures and comprehensive validation processes. Each cell line is subject to extensive characterization to confirm the successful knockout of the target gene, ensuring reliability in experimental outcomes. Unlike other products that may offer transient knockdown or less precise gene edits, our cell lines provide stable and consistent gene disruption, which is crucial for longer-term studies and reproducibility.

For researchers and clinicians seeking accurate and reliable tools for gene function studies, APOOL Gene Knockout Cell Lines represent an exceptional asset in experimental design. Their meticulous engineering combined with our commitment to high standards makes them an essential choice for advancing genetic research and therapeutic development.

At APOOL, we pride ourselves on our expertise in genetic engineering and commitment to providing high-quality biological products that empower scientific innovation, driving the future of research and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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