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APOL6 Knockout Cell Lines

Gene: APOL6

Official Full Name: apolipoprotein L6provided by HGNC

Gene Summary: This gene is a member of the apolipoprotein L gene family. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids or allow the binding of lipids to organelles. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25875 APOL6 Knockout cell line (A549) Human APOL6 1:3~1:4 Negative Online Inquiry

Background

APOL6 Gene Knockout Cell Lines are genetically engineered cell lines designed to exhibit a complete loss of function of the APOL6 gene, which encodes an essential protein involved in various biological processes, particularly in lipid metabolism and immune response. These cell lines are invaluable tools for researchers investigating the role of APOL6 in health and disease, allowing for in-depth studies on gene function, cellular signaling pathways, and interactions with other biomolecules.

The primary function of these knockout cell lines lies in their ability to eliminate APOL6 expression, thereby providing a controlled environment to study the gene's contributions to cellular behaviors, including apoptosis, proliferation, and inflammatory responses. By utilizing CRISPR technology, these cell lines ensure precise modification of the genome, allowing researchers to observe the differential effects of APOL6 depletion compared to wild-type cells. This mechanism facilitates the examination of the gene's involvement in diseases such as cancer and metabolic disorders.

The scientific significance of APOL6 Gene Knockout Cell Lines is profound, as they serve as a critical resource in both basic and translational research settings. Their applications extend to drug discovery, where they can help identify potential therapeutic targets, as well as in the assessment of gene therapies aimed at restoring normal function in mutated or dysfunctional genes.

What sets our APOL6 Gene Knockout Cell Lines apart is their high accuracy in gene editing and the reliability of the results obtained from experiments. Unlike other models that may show residual gene expression or variable responses, our knockout cell lines provide consistent and reproducible outcomes, significantly enhancing experimental integrity. This level of precision allows researchers to draw clearer conclusions and accelerate the translation of findings into clinical applications.

For researchers and clinicians alike, incorporating APOL6 Gene Knockout Cell Lines into experimental designs not only enhances the understanding of the biological role of APOL6 but also positions them at the forefront of innovative research, paving the way for breakthroughs in therapeutic interventions. Our company boasts a rich history in the development of cutting-edge genetic models, backed by a commitment to excellence and rigorous quality control, ensuring that you receive the most reliable biological tools tailored to meet your research needs.

Please note that all services are for research use only. Not intended for any clinical use.

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