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APIP Knockout Cell Lines

Gene: APIP

Official Full Name: APAF1 interacting proteinprovided by HGNC

Gene Summary: Enables identical protein binding activity; methylthioribulose 1-phosphate dehydratase activity; and zinc ion binding activity. Involved in several processes, including L-methionine salvage from methylthioadenosine; protein homotetramerization; and pyroptotic inflammatory response. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23107 APIP Knockout cell line (HeLa) Human APIP 1:3~1:6 Negative Online Inquiry
KO23108 APIP Knockout cell line (HCT 116) Human APIP 1:2~1:4 Negative Online Inquiry
KO23109 APIP Knockout cell line (HEK293) Human APIP 1:3~1:6 Negative Online Inquiry
KO23110 APIP Knockout cell line (A549) Human APIP 1:3~1:4 Negative Online Inquiry

Background

APIP Gene Knockout Cell Lines are genetically modified cellular models designed to facilitate precise gene function studies by selectively silencing the APIP gene. Utilizing advanced CRISPR-Cas9 technology, these cell lines enable researchers to create a specific gene knockout, resulting in the complete absence of the APIP protein. This innovative approach allows for detailed analyses of the biological roles and regulatory mechanisms of APIP in various cellular processes, including metabolic regulation, cell growth, and response to stressors.

The key functions of the APIP Gene Knockout Cell Lines stem from their ability to elucidate the contributions of APIP to cellular phenotypes, enhancing the understanding of its involvement in pathways related to oncogenesis and inflammation. By analyzing the functional outputs in these knockout models, researchers can derive insights into the gene’s role in specific disease mechanisms, paving the way for targeted therapeutic strategies or drug development.

In research and clinical contexts, these cell lines serve as essential tools for functional genomics, helping to pinpoint interactions with other cellular components and identifying potential biomarkers for diseases where APIP plays a pivotal role. Compared to traditional methods like RNA interference, the APIP knockout system provides a more stable and permanent alteration, leading to more reproducible results and long-term studies into gene function.

The distinct advantages of APIP Gene Knockout Cell Lines include their high specificity, ease of use, and versatility in various experimental setups, making them invaluable to both academia and biotechnology industries focused on genetic research. By using our innovative cell lines, researchers gain a clearer understanding of gene interactions and pathways, which can significantly expedite the development of novel therapies.

At the forefront of gene editing technology, our company brings extensive expertise in creating high-quality biological products tailored to meet the demands of contemporary research. With our APIP Gene Knockout Cell Lines, scientists are empowered to unlock new frontiers in genetic research and therapeutic innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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