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ANXA8L1 Knockout Cell Lines

Gene: ANXA8L1

Official Full Name: annexin A8 like 1provided by HGNC

Gene Summary: This gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin-specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10. [provided by RefSeq, Apr 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO19785 ANXA8L1 Knockout cell line (HeLa) Human ANXA8L1 1:3~1:6 Negative Online Inquiry
KO19786 ANXA8L1 Knockout cell line (A549) Human ANXA8L1 1:3~1:4 Negative Online Inquiry

Background

ANXA8L1 Gene Knockout Cell Lines are engineered cell lines specifically designed for the selective deletion of the annexin A8-like 1 (ANXA8L1) gene, known for its role in various cellular processes including membrane trafficking, apoptosis, and cell signaling. These knockout cell lines are indispensable tools for studying gene function, particularly in the context of cancer research and cellular response mechanisms.

The primary function of these cell lines is to enable researchers to observe the physiological and molecular consequences of ANXA8L1 gene deletion. By utilizing CRISPR-Cas9 technology or alternative genome editing methods, the deletion of this gene provides insights into its role in pathophysiological conditions. This mechanism allows researchers to pinpoint specific pathways influenced by ANXA8L1, facilitating a better understanding of disease states and potential therapeutic targets.

The scientific importance of ANXA8L1 Gene Knockout Cell Lines extends into numerous applications, from elucidating cell death pathways in oncogenesis to studying immune responses and cellular stress responses. In clinical settings, understanding how ANXA8L1 operates can pave the way for innovative cancer treatments and biomarker discovery, as the gene may serve as a potential target for therapeutic intervention.

Compared to alternative models such as wild-type cell lines or primary cells, ANXA8L1 Knockout Cell Lines offer distinct advantages. They provide a controlled environment to study gene-specific effects without the confounding variables present in native systems. Moreover, these specialized models allow for reproducibility and consistency in experiments, empowering researchers to draw more accurate conclusions.

For researchers and clinicians alike, the value of ANXA8L1 Gene Knockout Cell Lines lies in their ability to facilitate cutting-edge research with implications for therapeutic development. These cell lines not only accelerate discovery but also enhance understanding of complex biological processes, making them invaluable to any laboratory engaged in genetic, cellular, or cancer research.

As a leader in the field of biological products, our company is committed to providing high-quality, scientifically validated tools that foster innovation and advance research. Our expertise in gene editing technologies ensures that our offerings meet the rigorous demands of the scientific community, enhancing the potential for groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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