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ANXA4 Knockout Cell Lines

Gene: ANXA4

Official Full Name: annexin A4provided by HGNC

Gene Summary: Annexin IV (ANX4) belongs to the annexin family of calcium-dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. ANX4 has 45 to 59% identity with other members of its family and shares a similar size and exon-intron organization. Isolated from human placenta, ANX4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANX4 is almost exclusively expressed in epithelial cells. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO39002 ANXA4 Knockout cell line (HeLa) Human ANXA4 1:3~1:6 Negative Online Inquiry
KO39003 ANXA4 Knockout cell line (HCT 116) Human ANXA4 1:2~1:4 Negative Online Inquiry
KO39004 ANXA4 Knockout cell line (HEK293) Human ANXA4 1:3~1:6 Negative Online Inquiry
KO39005 ANXA4 Knockout cell line (A549) Human ANXA4 1:3~1:4 Negative Online Inquiry

Background

ANXA4 Gene Knockout Cell Lines are a vital tool in molecular biology that allow researchers to study the functional roles of the ANXA4 gene within various cellular contexts. These genetically modified cell lines have been engineered to lack the expression of the ANXA4 protein, providing a powerful system for investigating the impacts of ANXA4 loss on cellular behavior, signaling pathways, and disease mechanisms. By employing CRISPR/Cas9 or other gene-editing technologies, these knockout models facilitate the exploration of ANXA4's involvement in processes such as apoptosis, inflammation, and cell motility.

The utility of ANXA4 Gene Knockout Cell Lines extends to both research and clinical applications. In basic research, these models are invaluable for dissecting the biological functions of ANXA4 and its contribution to different diseases, including cancers and autoimmune disorders. The insights gained can lead to the identification of new therapeutic targets and the development of innovative treatment strategies. Clinically, this product is essential for testing potential drugs or interventions targeting the pathways influenced by ANXA4, ultimately aiding in translational research.

What sets our ANXA4 Gene Knockout Cell Lines apart is their high specificity and reliability, offering significant advantages over other gene knockout systems. These lines come with comprehensive validation protocols and detailed characterization, ensuring reproducibility in results and dependable performance for experimental designs. This level of quality allows researchers to confidently derive conclusions from their experiments, which is crucial for downstream applications.

For researchers and clinicians alike, ANXA4 Gene Knockout Cell Lines represent a cutting-edge resource that can accelerate scientific discovery and enhance understanding of gene functions in health and disease. Our company's commitment to excellence in biogenetics and cell line development guarantees that users receive not only high-quality products but also unmatched support in their research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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