Gene: ANXA13
Official Full Name: annexin A13provided by HGNC
Gene Summary: This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. The specific function of this gene has not yet been determined; however, it is associated with the plasma membrane of undifferentiated, proliferating endothelial cells and differentiated villus enterocytes. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO39001 | ANXA13 Knockout cell line (A549) | Human | ANXA13 | 1:3~1:4 | Negative | Online Inquiry |
ANXA13 Gene Knockout Cell Lines are genetically engineered cell lines that have been specifically designed to disrupt the expression of the annexin A13 gene (ANXA13), a member of the annexin family involved in various cellular processes, including proliferation, differentiation, and apoptosis. These cell lines serve as powerful tools for researchers to investigate the precise role of ANXA13 in cellular mechanisms and disease pathways.
The primary function of these knockout cell lines lies in their ability to enable the elucidation of ANXA13's contributions to cellular signaling and its implications in various pathological conditions, such as cancer and inflammatory diseases. By removing the ANXA13 gene, scientists can observe the resultant phenotypic changes, allowing for deeper insights into its physiological and pathological roles. The knockout approach provides a clear and direct means to study the effects of ANXA13 absence, thus offering opportunities for targeted therapeutic research and drug development.
In clinical and research settings, ANXA13 Gene Knockout Cell Lines are invaluable for their applications in understanding disease mechanisms and testing potential therapeutic interventions. They facilitate high-throughput drug screening, gene function studies, and cellular interaction assays, thus expediting the development of novel treatment strategies.
What sets these knockout cell lines apart from alternatives is their precision and reliability, achieved through state-of-the-art genome-editing technology, such as CRISPR/Cas9. Researchers can expect enhanced reproducibility in experimental results, which is essential for advancing the understanding of gene function and interaction in complex biological landscapes.
For researchers and clinicians focused on pathophysiological research, the ANXA13 Gene Knockout Cell Lines present significant value by offering a consistent and robust platform for exploration. The insights gained from utilizing these cell lines can inform therapeutic strategies and contribute to the development of targeted treatments in a range of diseases.
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Please note that all services are for research use only. Not intended for any clinical use.
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