Home / ANP32B Knockout Cell Lines

ANP32B Knockout Cell Lines

Gene: ANP32B

Official Full Name: acidic nuclear phosphoprotein 32 family member Bprovided by HGNC

Gene Summary: Enables RNA polymerase binding activity and histone binding activity. Involved in several processes, including nucleosome assembly; positive regulation of cysteine-type endopeptidase activity; and positive regulation of protein export from nucleus. Located in cytoplasm; nucleolus; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00009 ANP32B Knockout cell line (293T) Human ANP32B 1:3~1:6 Negative Online Inquiry

Background

ANP32B Gene Knockout Cell Lines are specially engineered cells in which the ANP32B gene has been deliberately disrupted or "knocked out." These cell lines are crucial tools for studying the biological roles of the ANP32B protein, which is known to be involved in various cellular processes, including apoptosis, transcription regulation, and responses to cellular stress. By creating these knockout models, researchers can assess the functional consequences of the loss of ANP32B, thereby elucidating its contribution to cellular homeostasis and disease mechanisms.

The key function of these cell lines lies in their ability to provide an in-depth view of the ANP32B gene's role within various biological pathways. The knockout strategy employed utilizes CRISPR/Cas9 technology, which allows for precise edits to the genome, ensuring that the resulting cell lines are devoid of the ANP32B gene. This specificity leads to robust and reproducible results in experimental settings. Researchers can utilize these cell lines for functional assays, drug discovery, and mechanistic studies that contribute to a better understanding of cancer biology, neurodegenerative diseases, and other pathological processes.

The scientific importance of ANP32B Gene Knockout Cell Lines extends into both research and clinical applications. In basic research, these models facilitate the exploration of gene function and provide insights into disease pathways. Clinically, they hold potential for therapeutic advancements by identifying novel drug targets or revealing biomarkers for disease prognosis.

What sets these knockout cell lines apart from alternatives is their high efficiency and versatility in experimental designs. Unlike traditional knockout methodologies that may exhibit off-target effects or varying knockout efficiency, our cell lines are rigorously validated for specificity and functionality, ensuring greater reliability in experimental outcomes.

For researchers and clinicians seeking reliable models for studying gene function, ANP32B Gene Knockout Cell Lines offer an invaluable resource that accelerates scientific discovery and aids in the development of innovative therapies. Our company specializes in providing high-quality biological products supported by extensive expertise in gene editing technologies, ensuring researchers are equipped with tools that enhance their understanding of complex biological systems.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.