Gene: ANKS6
Official Full Name: ankyrin repeat and sterile alpha motif domain containing 6provided by HGNC
Gene Summary: This gene encodes a protein containing multiple ankyrin repeats and a SAM domain. It is thought that this protein may localize to the proximal region of the primary cilium, and may play a role in renal and cardiovascular development. Mutations in this gene have been shown to cause a form of nephronophthisis (NPHP16), a chronic tubulo-interstitial nephritis. [provided by RefSeq, Jul 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO36007 | ANKS6 Knockout cell line (HeLa) | Human | ANKS6 | 1:3~1:6 | Negative | Online Inquiry |
KO36008 | ANKS6 Knockout cell line (HCT 116) | Human | ANKS6 | 1:2~1:4 | Negative | Online Inquiry |
KO36009 | ANKS6 Knockout cell line (HEK293) | Human | ANKS6 | 1:3~1:6 | Negative | Online Inquiry |
KO36010 | ANKS6 Knockout cell line (A549) | Human | ANKS6 | 1:3~1:4 | Negative | Online Inquiry |
ANKS6 Gene Knockout Cell Lines are specialized cell lines that have been genetically modified to disrupt the expression of the ANKS6 gene, which encodes a protein involved in critical cellular processes such as signal transduction, cellular differentiation, and immune response modulation. By utilizing a targeted gene knockout approach, these cell lines provide researchers with a powerful tool to study the functional implications of ANKS6 deficiency. The mechanism involves the use of CRISPR-Cas9 technology or RNA interference, which ensures precise alteration of the gene while maintaining the integrity of other genomic elements.
The scientific significance of ANKS6 knockout cell lines lies in their diverse applications across both basic and translational research. They are particularly valuable for investigating the role of ANKS6 in cellular pathways relevant to diseases such as cancer, autoimmune disorders, and neurodegeneration. The ability to analyze phenotypic changes and elucidate molecular mechanisms offers vital insights that can inform therapeutic strategies.
One of the primary advantages of ANKS6 Gene Knockout Cell Lines is the specificity of gene alteration, which reduces off-target effects often associated with traditional knockout methods. This specificity enables researchers to generate more reliable data, enhancing the reproducibility of experiments. Furthermore, these cell lines are readily available in various biological contexts, allowing for versatile applications in a wide range of experimental setups.
For researchers and clinicians, the value of ANKS6 knockout cell lines is underscored by their ability to drive innovative discoveries in gene function and disease modeling. These tools not only facilitate a deeper understanding of genetic contributions to pathology but also pave the way for the development of targeted therapies.
Our company is committed to advancing scientific research by providing high-quality biological products and expertise. With a focus on innovation and reliability, we empower researchers with the tools necessary to explore the complexities of gene function and disease mechanisms, thereby contributing to significant advancements in biomedical science.
Please note that all services are for research use only. Not intended for any clinical use.
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