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ANKS3 Knockout Cell Lines

Gene: ANKS3

Official Full Name: ankyrin repeat and sterile alpha motif domain containing 3provided by HGNC

Gene Summary: Predicted to be located in cytoplasm. Predicted to be active in cilium. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28058 ANKS3 Knockout cell line (HeLa) Human ANKS3 1:3~1:6 Negative Online Inquiry
KO28059 ANKS3 Knockout cell line (HCT 116) Human ANKS3 1:2~1:4 Negative Online Inquiry
KO28060 ANKS3 Knockout cell line (HEK293) Human ANKS3 1:3~1:6 Negative Online Inquiry
KO28061 ANKS3 Knockout cell line (A549) Human ANKS3 1:3~1:4 Negative Online Inquiry

Background

ANKS3 Gene Knockout Cell Lines are specially engineered cellular models that lack the expression of the ANKS3 gene, a critical component in various signaling pathways influencing cellular behavior, differentiation, and response to external stimuli. These knockout cell lines serve as vital tools in molecular biology research, allowing scientists to dissect the functional roles of the ANKS3 gene in cellular processes, disease mechanisms, and therapeutic responses.

The primary function of the ANKS3 knockouts is to enable the exploration of ANKS3's contribution to regulatory pathways within the cell. By comparing knockout cell lines to their wild-type counterparts, researchers can elucidate the gene’s role in processes like cellular growth, apoptosis, and response to stressors. Mechanistically, the absence of ANKS3 alters signaling cascades, impacting downstream effects on protein interactions and gene expression, thereby providing critical insights into signaling dynamics.

Scientifically, these cell lines hold immense importance for both basic and applied research. Their applications span various fields, including cancer research, neurobiology, and developmental biology, where understanding the role of genetic factors is essential for elucidating disease mechanisms and developing targeted therapies. Moreover, they serve as crucial models for investigating the efficacy of drugs and therapeutic interventions.

One of the key advantages of ANKS3 Gene Knockout Cell Lines is their specificity and reliability as experimental models. By utilizing CRISPR/Cas9 technology, these cell lines ensure precise gene disruption, leading to reproducible results that are crucial for drawing valid conclusions. In contrast to other methods, such as RNA interference, which can lead to off-target effects and partial knockdown, these knockout models provide a clean genetic background, enhancing experimental fidelity.

For researchers and clinicians, the value of ANKS3 Gene Knockout Cell Lines is magnified by their capability to facilitate groundbreaking discoveries in gene function and disease pathology. The insights gained from these models can profoundly influence the development of novel diagnostic tools and innovative treatments, empowering scientists to advance the frontiers of knowledge in genetics and cell biology.

Our company specializes in providing high-quality biological products, with a strong commitment to advancing scientific research. Our experienced team employs cutting-edge technologies to create reliable tools like the ANKS3 Gene Knockout Cell Lines, tailored to meet the evolving needs of researchers and clinical investigators.

Please note that all services are for research use only. Not intended for any clinical use.

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