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ANKRD26 Knockout Cell Lines

Gene: ANKRD26

Official Full Name: ankyrin repeat domain containing 26provided by HGNC

Gene Summary: This gene encodes a protein containing N-terminal ankyrin repeats which function in protein-protein interactions. Mutations in this gene are associated with autosomal dominant thrombocytopenia-2. Pseudogenes of this gene are found on chromosome 7, 10, 13 and 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30276 ANKRD26 Knockout cell line (HeLa) Human ANKRD26 1:3~1:6 Negative Online Inquiry
KO30277 ANKRD26 Knockout cell line (HCT 116) Human ANKRD26 1:2~1:4 Negative Online Inquiry
KO30278 ANKRD26 Knockout cell line (HEK293) Human ANKRD26 1:3~1:6 Negative Online Inquiry
KO30279 ANKRD26 Knockout cell line (A549) Human ANKRD26 1:3~1:4 Negative Online Inquiry

Background

ANKRD26 Gene Knockout Cell Lines are genetically engineered cellular models that have been specifically designed to lack the expression of the ANKRD26 gene. This gene is implicated in a range of biological processes, including hematopoiesis and cell-signaling pathways. By utilizing CRISPR-Cas9 technology or other state-of-the-art gene-editing techniques, these knockout cell lines facilitate the study of gene function and the biological consequences of ANKRD26 deficiency.

The primary function of ANKRD26 Gene Knockout Cell Lines lies in their ability to serve as a valuable tool for researchers investigating the role of the ANKRD26 gene in normal and pathological contexts. These cell lines provide insights into gene regulatory networks, cellular differentiation, and the implications of ANKRD26 mutations in diseases like aplastic anemia and leukemia. Moreover, they enable researchers to explore novel therapeutic targets and to gain a deeper understanding of cellular response mechanisms related to this critical gene.

In the realm of scientific research, ANKRD26 knockout models are pivotal for elucidating the contributions of this gene in various cellular processes. Compared to alternatives such as wild-type or other genetically modified cell lines, the ANKRD26 knockout models uniquely offer complete gene disruption, allowing for clear observations of phenotypic changes in response to environmental stimuli and treatments.

For clinical applications, these cell lines are indispensable in drug discovery and development, providing a more accurate representation of patient-specific responses when studying treatments or therapies that may affect hematological disorders. Their availability allows researchers and clinicians to refine preclinical models, leading to more reliable and translatable results.

By utilizing our ANKRD26 Gene Knockout Cell Lines, researchers will benefit from a meticulously validated product that enhances experimental reproducibility and accuracy. With a commitment to advancing the field, our company brings a wealth of expertise in gene editing and cell line development, ensuring that our products support groundbreaking discoveries in molecular biology and contribute to significant clinical advancements.

Please note that all services are for research use only. Not intended for any clinical use.

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