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ANKRD18A Knockout Cell Lines

Gene: ANKRD18A

Official Full Name: ankyrin repeat domain 18Aprovided by HGNC

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21219 ANKRD18A Knockout cell line (HeLa) Human ANKRD18A 1:3~1:6 Negative Online Inquiry
KO21220 ANKRD18A Knockout cell line (HCT 116) Human ANKRD18A 1:2~1:4 Negative Online Inquiry
KO21221 ANKRD18A Knockout cell line (HEK293) Human ANKRD18A 1:3~1:6 Negative Online Inquiry
KO21222 ANKRD18A Knockout cell line (A549) Human ANKRD18A 1:3~1:4 Negative Online Inquiry

Background

ANKRD18A Gene Knockout Cell Lines are specialized cellular systems engineered for the precise disruption of the ANKRD18A gene, which encodes a protein implicated in various cellular functions, including cell signaling and protein interactions. These knockout cell lines enable researchers to study the specific roles of ANKRD18A in cellular processes by providing a model to evaluate gene function in a controlled environment.

The core mechanism of these knockout cell lines revolves around CRISPR/Cas9 technology, allowing for specific and efficient editing of the ANKRD18A gene. This gene editing results in frameshift mutations, leading to the loss of ANKRD18A protein expression, thus enabling the investigation of the consequent phenotypic and molecular changes. As ANKRD18A is associated with several pathways critical for cellular homeostasis and stress response, these knockout models serve as powerful tools in dissecting disease mechanisms, particularly in cancer and other biological contexts.

The scientific significance of ANKRD18A knockout cell lines extends to both basic research and clinical applications. Researchers can utilize these models for high-throughput screening, drug discovery, and mechanistic studies that seek to understand how disruptions of this gene can contribute to pathological states. Moreover, these models facilitate the assessment of potential therapeutic targets, illuminating novel approaches in regenerative medicine and personalized therapies.

Compared to alternative models that may only partially recapitulate gene function, our ANKRD18A knockout cell lines offer unparalleled specificity and reliability for studying the multifaceted roles of the ANKRD18A protein. This targeted approach reduces the complexities associated with noise in gene expression and enhances the fidelity of findings pertaining to gene function and interaction networks.

For researchers, clinicians, and pharmaceutical companies, the value of ANKRD18A Gene Knockout Cell Lines lies not only in their technical sophistication but in their capacity to advance our understanding of critical biological processes. By leveraging these cells, professionals can accelerate their research and development timelines, ultimately contributing to the advancement of therapeutic interventions.

At [Your Company Name], we specialize in generating high-quality, custom cell lines tailored to meet the specific demands of modern biological research. Our commitment to excellence ensures that you have access to the most advanced tools and resources in gene editing and cellular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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