Gene: ANKRD13C
Official Full Name: ankyrin repeat domain 13Cprovided by HGNC
Gene Summary: Enables signaling receptor binding activity. Involved in protein retention in ER lumen; regulation of anoikis; and regulation of signaling receptor activity. Located in endoplasmic reticulum and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25717 | ANKRD13C Knockout cell line (HeLa) | Human | ANKRD13C | 1:3~1:6 | Negative | Online Inquiry |
KO25718 | ANKRD13C Knockout cell line (HCT 116) | Human | ANKRD13C | 1:2~1:4 | Negative | Online Inquiry |
KO25719 | ANKRD13C Knockout cell line (HEK293) | Human | ANKRD13C | 1:3~1:6 | Negative | Online Inquiry |
KO25720 | ANKRD13C Knockout cell line (A549) | Human | ANKRD13C | 1:3~1:4 | Negative | Online Inquiry |
ANKRD13C Gene Knockout Cell Lines are expertly crafted cellular models that specifically target the Ankyrin Repeat Domain-containing protein 13C (ANKRD13C), a critical component involved in intracellular trafficking and vesicle transport. These genetically engineered cell lines have been created using precise CRISPR-Cas9 technology, allowing for the successful knockout of the ANKRD13C gene, which is pivotal in various physiological processes, including endocytosis and neurodevelopmental pathways.
The functional mechanism of ANKRD13C encompasses its role in the sorting and trafficking of proteins, particularly in the context of membrane dynamics and recycling processes. By employing these knockout cell lines, researchers can elucidate the specific contributions of ANKRD13C to cellular functions, providing a clearer understanding of its role in diseases such as cancer and neurological disorders.
In terms of scientific significance, these cell lines serve as invaluable tools in both research and clinical settings. They facilitate advanced studies on cellular signaling pathways and their implications in pathophysiology, allowing for high-throughput screenings of therapeutic targets and the assessment of drug efficacy. Additionally, they enable the exploration of molecular interactions and the characterization of the impact of ANKRD13C loss on cellular behavior.
Compared to traditional wild-type cell lines, ANKRD13C Gene Knockout Cell Lines offer distinct advantages, including enhanced specificity in studying gene function and the ability to generate more relevant data in contexts specific to the ANKRD13C pathway. This specificity elevates the quality and applicability of the research findings, making it easier to translate discoveries into potential clinical applications.
For researchers and clinicians aiming to gain insights into complex biological systems or develop innovative therapeutic strategies, these knockout cell lines represent a powerful resource. The product is backed by our company’s extensive expertise in genetic engineering and molecular biology, ensuring that our offerings are of the highest quality and relevance in advancing scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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