Gene: ANKRD10
Official Full Name: ankyrin repeat domain 10provided by HGNC
Gene Summary: Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19855 | ANKRD10 Knockout cell line (HeLa) | Human | ANKRD10 | 1:3~1:6 | Negative | Online Inquiry |
KO19856 | ANKRD10 Knockout cell line (HCT 116) | Human | ANKRD10 | 1:2~1:4 | Negative | Online Inquiry |
KO19857 | ANKRD10 Knockout cell line (HEK293) | Human | ANKRD10 | 1:3~1:6 | Negative | Online Inquiry |
KO19858 | ANKRD10 Knockout cell line (A549) | Human | ANKRD10 | 1:3~1:4 | Negative | Online Inquiry |
ANKRD10 Gene Knockout Cell Lines represent a cutting-edge tool in molecular biology that provides researchers with the ability to elucidate the role of the ANKRD10 gene in various biological processes. These specialized cell lines are engineered using CRISPR-Cas9 gene editing technology to achieve a complete disruption of the ANKRD10 gene, leading to the loss of its associated protein product. This precise genetic alteration allows for enhanced study of ANKRD10's functions, interactions, and implications in both physiological and pathological contexts.
The primary mechanism of action involves the targeted introduction of double-strand breaks in the ANKRD10 genomic sequence, followed by cellular repair processes that result in gene knockout. By studying these knockout cell lines, scientists can investigate the gene's involvement in cellular pathways such as cell cycle regulation, apoptosis, and cellular stress responses, giving insights into diseases where ANKRD10 may play a critical role, including cancer and developmental disorders.
The scientific importance of ANKRD10 Gene Knockout Cell Lines is profound, as they facilitate the examination of gene function in vitro, providing a valuable model system that can complement in vivo studies. The diverse applications span research domains, including developmental biology, genetics, and pharmacology, making these knockout lines vital for drug discovery and therapeutic intervention studies.
Compared to alternative models, such as transient knockdown approaches or RNA interference methods, ANKRD10 Gene Knockout Cell Lines offer permanent and stable gene disruption. This permanence allows for consistent experimental conditions and higher reproducibility of results, which are paramount for reliable scientific findings. Additionally, the ability to analyze long-term cellular behaviors and interactions in the absence of ANKRD10 enhances the depth of functional insights that can be gathered.
For researchers and clinicians, the value of these knockout cell lines is unequivocal, as they not only streamline the investigation of gene function but also open avenues for therapeutic development targeted at diseases linked to ANKRD10 dysregulation. Utilizing ANKRD10 Gene Knockout Cell Lines can significantly accelerate hypothesis testing and lead to breakthroughs in understanding gene-related disorders.
With a commitment to advancing biological research, our company prides itself on a robust portfolio of high-quality genetic models and innovative solutions tailored for the scientific community. Through our expertise in gene editing technologies and commitment to scientific excellence, we strive to support researchers in their quest for knowledge and discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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