Gene: ANGEL1
Official Full Name: angel homolog 1provided by HGNC
Gene Summary: Enables eukaryotic initiation factor 4E binding activity and protein domain specific binding activity. Located in several cellular components, including cis-Golgi network; endoplasmic reticulum; and perinuclear region of cytoplasm. Is active in mitochondrial outer membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29389 | ANGEL1 Knockout cell line (HeLa) | Human | ANGEL1 | 1:3~1:6 | Negative | Online Inquiry |
KO29390 | ANGEL1 Knockout cell line (HCT 116) | Human | ANGEL1 | 1:2~1:4 | Negative | Online Inquiry |
KO29391 | ANGEL1 Knockout cell line (HEK293) | Human | ANGEL1 | 1:3~1:6 | Negative | Online Inquiry |
KO29392 | ANGEL1 Knockout cell line (A549) | Human | ANGEL1 | 1:3~1:4 | Negative | Online Inquiry |
ANGEL1 Gene Knockout Cell Lines are genetically modified cellular models designed to enhance the understanding of ANGEL1 gene functions and their implications in various biological processes. Created through advanced CRISPR-Cas9 technology, these cell lines exhibit complete knockout of the ANGEL1 gene, thereby enabling researchers to investigate the physiological and pathological roles of this gene in cellular mechanisms, signaling pathways, and disease states.
The primary function of ANGEL1 gene knockout cell lines lies in their ability to facilitate the study of gene function by providing a clear contrast between normal gene expression and gene deficiency. By disrupting the ANGEL1 gene, these cell lines allow for the exploration of changes in cellular behavior, including alterations in proliferation, differentiation, and response to external stimuli. This knockout model is particularly valuable in understanding the role of ANGEL1 in diseases where its dysregulation is implicated, such as certain cancers and genetic disorders.
In scientific research and clinical settings, ANGEL1 gene knockout cell lines serve as pivotal tools for drug discovery, gene function validation, and the development of targeted therapies. Their ability to mimic disease-relevant conditions allows for high-throughput screening of therapeutic compounds, leading to the identification of novel interventions that could alleviate disease symptoms or target malignant cells.
A significant advantage of using ANGEL1 gene knockout cell lines over traditional models is their precise genomic editing, which minimizes off-target effects and enhances the reliability of experimental results. Additionally, these cell lines can be easily maintained and manipulated by researchers, making them an ideal choice for extensive studies in cellular biology and pharmacology.
For researchers, clinicians, and biopharmaceutical companies seeking reliable models for gene analysis and therapeutic development, ANGEL1 gene knockout cell lines provide a valuable asset for their experimental toolkit. The growing body of literature supporting their crucial role in gene function studies underscores their scientific importance.
Our company excels in developing high-quality, genetically modified cell lines, reflecting our commitment to advancing biomedical research. With cutting-edge technology and a focus on user-friendly products, we empower scientists to explore the complexities of genetics and disease at an unprecedented level.
Please note that all services are for research use only. Not intended for any clinical use.
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