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ANAPC16 Knockout Cell Lines

Gene: ANAPC16

Official Full Name: anaphase promoting complex subunit 16provided by HGNC

Gene Summary: Involved in anaphase-promoting complex-dependent catabolic process and protein polyubiquitination. Located in cytosol and kinetochore. Part of anaphase-promoting complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30367 ANAPC16 Knockout cell line (HeLa) Human ANAPC16 1:3~1:6 Negative Online Inquiry
KO30368 ANAPC16 Knockout cell line (HCT 116) Human ANAPC16 1:2~1:4 Negative Online Inquiry
KO30369 ANAPC16 Knockout cell line (HEK293) Human ANAPC16 1:3~1:6 Negative Online Inquiry
KO30370 ANAPC16 Knockout cell line (A549) Human ANAPC16 1:3~1:4 Negative Online Inquiry

Background

ANAPC16 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to facilitate the study of the ANAPC16 gene, recognized for its role in cell cycle regulation and tumorigenesis. These cell lines serve as critical tools for investigating the functional implications of ANAPC16 deletion in various biological contexts, including cancer research and developmental biology. By providing a model wherein the gene is completely knocked out, researchers can explore the downstream effects on cellular behavior, protein interactions, and regulatory networks.

The core mechanism behind the ANAPC16 Gene Knockout Cell Lines lies in the CRISPR-Cas9 genome editing technology, allowing for precise and efficient gene disruption. This results in the complete loss of function of the ANAPC16 protein, enabling detailed studies on cell proliferation, differentiation, and apoptosis in a controlled environment. The knockout model mirrors physiological conditions, making it an invaluable resource for understanding the gene's involvement in pathologies associated with cell cycle dysregulation.

Scientifically, these cell lines hold immense significance, particularly in oncology and genetic research. The insights garnered from utilizing ANAPC16 knockout models can elucidate its role in cancer development and progression, potentially guiding therapeutic strategies and biomarker identification. In clinical settings, such models enable the evaluation of drug responsiveness and the identification of novel treatment targets, thereby accelerating the translation of research findings to patient care.

Distinct advantages of ANAPC16 Gene Knockout Cell Lines include their robustness and reproducibility in experimental setups, as well as their compatibility with high-throughput screening assays, which can streamline the drug discovery process compared to other knockout models. Unlike traditional methods that may rely on transient transfection or partial knockdowns, these stable lines offer a consistent background for comparing phenotypic outcomes, enhancing data reliability.

For researchers and clinicians alike, ANAPC16 Gene Knockout Cell Lines provide a cutting-edge solution capable of revealing the complexities of gene function in health and disease. Our commitment to advancing genetic research is backed by our deep expertise in genomic technologies and a comprehensive portfolio of biological products. We strive to equip the scientific community with tools that can drive novel discoveries and improve therapeutic outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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