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AMIGO1 Knockout Cell Lines

Gene: AMIGO1

Official Full Name: adhesion molecule with Ig like domain 1provided by HGNC

Gene Summary: Predicted to enable potassium channel regulator activity. Predicted to be involved in several processes, including heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; nervous system development; and positive regulation of nervous system development. Predicted to be located in dendrite; neuronal cell body membrane; and voltage-gated potassium channel complex. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO19879 AMIGO1 Knockout cell line (HeLa) Human AMIGO1 1:3~1:6 Negative Online Inquiry
KO19880 AMIGO1 Knockout cell line (A549) Human AMIGO1 1:3~1:4 Negative Online Inquiry

Background

AMIGO1 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the AMIGO1 gene, which encodes a member of the immunoglobulin superfamily involved in neuronal and immune system functions. These cell lines provide researchers with a powerful tool for investigating the role of AMIGO1 in cellular processes such as adhesion, migration, and signal transduction. The gene knockout is achieved through advanced CRISPR-Cas9 technology, ensuring precise and efficient alteration of the genome, which allows for the study of the biological consequences of its absence in various experimental contexts.

The AMIGO1 Gene Knockout Cell Lines serve as significant models in both fundamental and applied biological research. They facilitate the investigation into the gene's involvement in neural development, immune response regulation, and potential implications in neurodegenerative diseases. In addition, these cell lines can be utilized in drug screening and therapeutic development, offering insights into how targeting AMIGO1 pathways may influence cellular behavior in pathological conditions.

Compared to traditional cell lines or methods that rely on transient knockdown, the AMIGO1 Gene Knockout Cell Lines provide a stable, controlled genetic background, promoting reproducibility and reliability in experimental outcomes. This stability allows for long-term experiments and a more accurate assessment of how AMIGO1 deletion affects cellular functions.

For researchers and clinicians focused on neurobiology, immunology, or regenerative medicine, these cell lines offer a unique advantage by enabling in-depth exploration of molecular mechanisms that drive health and disease. Their use can lead to novel insights and innovations in therapeutic approaches.

Our company prides itself on delivering high-quality, meticulously validated biological products, combined with an expertise in cutting-edge genome editing technologies. We are committed to advancing scientific research and clinical applications by providing reliable tools like the AMIGO1 Gene Knockout Cell Lines to facilitate groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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