Gene: AMER1
Official Full Name: APC membrane recruitment protein 1provided by HGNC
Gene Summary: The protein encoded by this gene upregulates trancriptional activation by the Wilms tumor protein and interacts with many other proteins, including CTNNB1, APC, AXIN1, and AXIN2. Defects in this gene are a cause of osteopathia striata with cranial sclerosis (OSCS). [provided by RefSeq, May 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO07105 | AMER1 Knockout cell line (HeLa) | Human | AMER1 | 1:3~1:6 | Negative | Online Inquiry |
KO07106 | AMER1 Knockout cell line (HCT 116) | Human | AMER1 | 1:2~1:4 | Negative | Online Inquiry |
KO07107 | AMER1 Knockout cell line (HEK293) | Human | AMER1 | 1:3~1:6 | Negative | Online Inquiry |
KO07108 | AMER1 Knockout cell line (A549) | Human | AMER1 | 1:3~1:4 | Negative | Online Inquiry |
AMER1 Gene Knockout Cell Lines are meticulously engineered cellular models designed to facilitate the study of the AMER1 gene's role in cellular functions and disease mechanisms. By employing CRISPR-Cas9 technology, these cell lines exhibit a complete knockout of the AMER1 gene, allowing researchers to investigate the gene's impact on cellular pathways, tumorigenesis, and developmental processes.
The main function of these knockout cell lines is to provide a clear framework for assessing the consequences of AMER1 loss, particularly in the context of cancer research. AMER1 has been implicated in cellular adhesion and signaling pathways, making it crucial for understanding the underlying mechanisms of malignancy. The knockout model enables scientists to delineate the gene's role by examining phenotypic changes, alterations in gene expression, and responses to external stimuli in a controlled environment.
From a scientific standpoint, AMER1 Gene Knockout Cell Lines are invaluable in both basic and applied research settings. They serve as powerful tools for elucidating the molecular pathways associated with various cancers, thus driving the development of targeted therapeutics. Furthermore, these cell lines can be used in drug discovery processes, enhancing the identification of potential therapeutic agents that can modulate the activities influenced by AMER1.
What sets our AMER1 Gene Knockout Cell Lines apart is their rigorous validation and quality assurance. Unlike other alternatives available on the market, our product has undergone extensive characterization, ensuring that the knockout is stable and reproducible across different passages. This reliability allows researchers to draw more accurate conclusions from their experiments.
For researchers and clinicians, these cell lines represent not just a product, but a gateway to deeper biological insights that can influence both experimental outcomes and patient treatments. By integrating these models into your research portfolio, you gain access to a tool that empowers innovative discoveries in the field of genetics and cancer biology.
Our company specializes in providing high-quality biological models and solutions, backed by leading-edge scientific expertise. With a commitment to excellence, we ensure our products meet the diverse needs of researchers and clinicians, positioning them at the forefront of their fields.
Please note that all services are for research use only. Not intended for any clinical use.
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