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ALS2CL Knockout Cell Lines

Gene: ALS2CL

Official Full Name: ALS2 C-terminal likeprovided by HGNC

Gene Summary: Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in endosomal transport. Predicted to act upstream of or within protein localization. Predicted to be located in cytosol. Predicted to be active in cytoplasmic vesicle. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO19881 ALS2CL Knockout cell line (HeLa) Human ALS2CL 1:3~1:6 Negative Online Inquiry
KO19882 ALS2CL Knockout cell line (HCT 116) Human ALS2CL 1:2~1:4 Negative Online Inquiry
KO19883 ALS2CL Knockout cell line (A549) Human ALS2CL 1:3~1:4 Negative Online Inquiry

Background

ALS2CL Gene Knockout Cell Lines are specialized cellular models designed to facilitate the study of the ALS2CL gene and its role in cellular functions, pathologies, and mechanisms related to various diseases. These cell lines have been genetically modified to disrupt the expression of the ALS2CL gene, allowing researchers to investigate the resulting phenotypic changes and understand the biological pathways influenced by this gene.

The primary function of ALS2CL is associated with cellular differentiation and growth regulation within the context of various tissues, especially in neurogenesis and neurological disorders. By utilizing ALS2CL knockout cell lines, researchers can untangle complex interactions and signaling pathways that are altered in the absence of this gene. This is particularly valuable in studies focusing on neurodegenerative diseases, where understanding gene functionality can reveal novel therapeutic targets and biomarkers.

The scientific importance of ALS2CL knockout cell lines cannot be overstated. They serve as critical tools in preclinical research, allowing for the validation of hypotheses and the exploration of gene-related processes in a controlled environment. These cell lines are especially relevant in drug discovery programs and the development of personalized medicine strategies, where targeted gene editing approaches are becoming increasingly pivotal.

Compared to traditional wild-type cell lines, ALS2CL knockout models offer a unique advantage by providing clearer insights into gene function through the lens of gene disruption. This specific knockout strategy allows researchers to obtain data that is more directly correlated to ALS2CL’s physiological roles, enabling more robust conclusions and reducing ambiguities often associated with other models.

Researchers, clinicians, and biopharmaceutical companies will find value in using ALS2CL knockout cell lines, as they enable the exploration of gene-gene interactions and the elucidation of underlying mechanisms of disease progression. This can accelerate the development of innovative treatments and improve the understanding of genetic contributions to health and disease.

Our company prides itself on its expertise in creating high-quality genetic models that empower scientific discovery and innovation. With a commitment to precision and reproducibility, we provide researchers with the tools necessary to drive their studies forward and ultimately contribute to the advancement of biomedical science.

Please note that all services are for research use only. Not intended for any clinical use.

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