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ALDOC Knockout Cell Lines

Gene: ALDOC

Official Full Name: aldolase, fructose-bisphosphate Cprovided by HGNC

Gene Summary: This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO08245 ALDOC Knockout cell line (HeLa) Human ALDOC 1:3~1:6 Negative Online Inquiry
KO08246 ALDOC Knockout cell line (HCT 116) Human ALDOC 1:2~1:4 Negative Online Inquiry
KO08247 ALDOC Knockout cell line (HEK293) Human ALDOC 1:3~1:6 Negative Online Inquiry
KO08248 ALDOC Knockout cell line (A549) Human ALDOC 1:3~1:4 Negative Online Inquiry

Background

ALDOC Gene Knockout Cell Lines are genetically modified cell lines specifically designed to facilitate the study of the Aldolase C gene (ALDOC). These cell lines enable researchers to investigate the biological roles of ALDOC by eliminating its expression through CRISPR/Cas9 gene editing technologies. The key function of these cell lines is to serve as a robust model for understanding metabolic pathways, cellular processes, and the physiological impacts associated with ALDOC deletion.

The mechanism by which ALDOC Gene Knockout Cell Lines operate involves precise genetic editing that ensures the complete removal of ALDOC RNA, leading to a functional knockout of the protein product. This creates a unique environment where researchers can explore the gene's involvement in critical processes such as glucose metabolism and neurological function, thus contributing valuable insights into conditions such as diabetes and neurological disorders.

The scientific importance of ALDOC Gene Knockout Cell Lines is underscored by their applications in both research and clinical settings. Researchers can utilize these cell lines to better understand metabolic disorders and develop targeted therapies. In a clinical context, they can be employed to investigate patient-specific responses to treatments, ultimately paving the way for personalized medicine.

Compared to traditional cell lines, these knockout models offer significant advantages, including a clear genetic background free from confounding variables and the ability for reproducible and high-throughput screening. This specificity allows researchers to achieve more nuanced results and enhance the reliability of their findings.

For researchers, clinicians, and laboratories, ALDOC Gene Knockout Cell Lines represent a valuable resource, addressing the growing demand for precise and reliable genetic tools in biomedical research. By providing these innovative cell lines, we affirm our commitment to advancing scientific discovery and our expertise in delivering high-quality biological products that underpin lifesaving research.

Please note that all services are for research use only. Not intended for any clinical use.

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