Gene: ALDH3B1
Official Full Name: aldehyde dehydrogenase 3 family member B1provided by HGNC
Gene Summary: This gene encodes a member of the aldehyde dehydrogenase protein family. Aldehyde dehydrogenases are a family of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The encoded protein is able to oxidize long-chain fatty aldehydes in vitro, and may play a role in protection from oxidative stress. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO39037 | ALDH3B1 Knockout cell line (HeLa) | Human | ALDH3B1 | 1:3~1:6 | Negative | Online Inquiry |
KO39038 | ALDH3B1 Knockout cell line (HCT 116) | Human | ALDH3B1 | 1:2~1:4 | Negative | Online Inquiry |
KO39039 | ALDH3B1 Knockout cell line (HEK293) | Human | ALDH3B1 | 1:3~1:6 | Negative | Online Inquiry |
KO39040 | ALDH3B1 Knockout cell line (A549) | Human | ALDH3B1 | 1:3~1:4 | Negative | Online Inquiry |
ALDH3B1 Gene Knockout Cell Lines are uniquely developed human-derived cell lines in which the ALDH3B1 gene has been specifically disrupted through CRISPR-Cas9 technology. This product serves as a vital tool for researchers exploring the physiological roles and biochemical pathways associated with aldehyde dehydrogenases, particularly the ALDH3B1 enzyme, which is known to play a crucial role in cellular detoxification processes and the metabolism of various endogenous and exogenous aldehydes.
The key function of these knockout cell lines is to facilitate in-depth studies into the effects of ALDH3B1 loss on cell viability, metabolic profiling, and stress response mechanisms. By comparing these knockout lines with wild-type cells, researchers can unearth insights about the influence of ALDH3B1 on oxidative stress, cancer cell proliferation, and drug metabolism, making them invaluable in pharmacological and toxicological research settings.
Scientifically, ALDH3B1 has implications in various diseases, including cancer and neurodegenerative disorders, positioning these cell lines as essential tools in the development of therapeutic strategies. Their application extends beyond basic research; in clinical settings, they can assist in biomarker identification and personalized medicine, allowing for tailored treatment approaches based on an individual’s metabolic profiles.
What sets our ALDH3B1 Gene Knockout Cell Lines apart from alternative products is the rigorous validation of gene targeting efficacy and functional characterization, ensuring that researchers can rely on consistent and reproducible results. Furthermore, our product is supported by extensive protocols and expert guidance, which significantly enhances the user's experience.
For researchers and clinicians aiming to advance their understanding of aldehyde metabolism and its implications in health and disease, our ALDH3B1 Gene Knockout Cell Lines are an essential addition to their toolkit. With years of expertise in genetic engineering and cell culture technology, we pride ourselves on providing high-quality biological products that accelerate discovery and innovation in life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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