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AK8 Knockout Cell Lines

Gene: AK8

Official Full Name: adenylate kinase 8provided by HGNC

Gene Summary: Enables AMP binding activity and nucleobase-containing compound kinase activity. Predicted to be involved in nucleoside monophosphate phosphorylation. Predicted to act upstream of or within ventricular system development. Located in 9+2 motile cilium. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO19919 AK8 Knockout cell line (HCT 116) Human AK8 1:2~1:4 Negative Online Inquiry

Background

AK8 Gene Knockout Cell Lines are advanced biological tools designed for targeted gene disruption, allowing researchers to study gene function and the resulting phenotypic effects comprehensively. These cell lines are engineered using CRISPR-Cas9 technology, a highly precise gene-editing tool that facilitates the knockout of specific genes of interest, resulting in loss-of-function models. By disabling selected genes, researchers can delineate the roles these genes play in various biological processes, including cell signaling, development, and disease mechanisms.

The AK8 Gene Knockout Cell Lines operate on a mechanism that harnesses the natural DNA repair processes within eukaryotic cells. Upon creating targeted double-strand breaks in the DNA at specified genomic locations, the cell's repair machinery often introduces insertions or deletions during the repair process, effectively disrupting the gene's functionality. This allows for the study of gene relevance in diseases such as cancer, neurological disorders, and metabolic syndromes.

The scientific importance of these cell lines is underscored by their applications in both basic and translational research settings. They enable researchers to create more accurate disease models, facilitating drug discovery and personalized medicine approaches. Notably, AK8 Gene Knockout Cell Lines stand out from alternative gene-editing products by offering validated genetic modifications with proven efficiency, robust reproducibility, and extensive characterization to ensure consistency across experiments.

For researchers and clinicians, the AK8 Gene Knockout Cell Lines provide a valuable resource to explore genetic contributions to disease and therapeutic responses. Their ease of use and integration into high-throughput screening platforms further enhance their appeal. By choosing AK8, users leverage our commitment to delivering high-quality biological products backed by years of expertise in the field. Our comprehensive quality assurance processes ensure that each product meets rigorous scientific standards, making AK8 Gene Knockout Cell Lines a pivotal asset in cutting-edge research.

Please note that all services are for research use only. Not intended for any clinical use.

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