Gene: AK5
Official Full Name: adenylate kinase 5provided by HGNC
Gene Summary: This gene encodes a member of the adenylate kinase family, which is involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. This member is related to the UMP/CMP kinase of several species. It is located in the cytosol and expressed exclusively in brain. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28135 | AK5 Knockout cell line (HEK293) | Human | AK5 | 1:3~1:6 | Negative | Online Inquiry |
KO28136 | AK5 Knockout cell line (A549) | Human | AK5 | 1:3~1:4 | Negative | Online Inquiry |
AK5 Gene Knockout Cell Lines are a revolutionary tool designed for the in-depth study of gene function and its associated pathways. These cell lines are specifically engineered to disable the AK5 gene, a crucial player in adenine nucleotide metabolism, enabling researchers to explore the physiological consequences of its loss. By creating a controlled environment wherein the AK5 gene is knocked out, scientists can accurately assess the gene's roles in various biological processes, including energy production, metabolic regulation, and cellular signaling pathways.
The primary function of AK5 Gene Knockout Cell Lines lies in their ability to facilitate the investigation of AK5's biochemical interactions and the resultant effects on cellular physiology. This is achieved through techniques like gene editing, which utilizes CRISPR/Cas9 technology to ensure precise disruption of the AK5 gene. Consequently, researchers can observe alterations in cell proliferation, apoptosis, and metabolic shifts, contributing to a better understanding of diseases related to nucleotide metabolism.
Scientifically, these knockout cell lines hold immense importance in both research and clinical settings. They serve as invaluable models for studying metabolic disorders, cancer, and other conditions where nucleotide homeostasis plays a critical role. These studies could lead to potential therapeutic targets and personalized medicine strategies, significantly enhancing patient outcomes.
What sets AK5 Gene Knockout Cell Lines apart from alternative products is their exceptional specificity and reliability. Each cell line undergoes comprehensive validation to confirm the effective knockout of the AK5 gene, ensuring that researchers are working with robust models. Additionally, their easy adaptability for high-throughput screening makes them a practical choice for large-scale studies, saving time and resources in the research process.
For researchers, clinicians, and biotechnology companies, the AK5 Gene Knockout Cell Lines offer profound value, enabling a deeper exploration of gene function and the potential development of breakthrough therapies. By choosing our product, users benefit from our company’s extensive expertise in cellular biology and genetic engineering, ensuring that they receive top-tier scientific resources that align with their research goals.
Please note that all services are for research use only. Not intended for any clinical use.
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