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AIF1L Knockout Cell Lines

Gene: AIF1L

Official Full Name: allograft inflammatory factor 1 likeprovided by HGNC

Gene Summary: Enables actin filament binding activity. Predicted to be involved in actin filament bundle assembly and ruffle assembly. Located in actin filament and focal adhesion. Biomarker of breast cancer. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25466 AIF1L Knockout cell line (HeLa) Human AIF1L 1:3~1:6 Negative Online Inquiry
KO25467 AIF1L Knockout cell line (HCT 116) Human AIF1L 1:2~1:4 Negative Online Inquiry
KO25468 AIF1L Knockout cell line (HEK293) Human AIF1L 1:3~1:6 Negative Online Inquiry
KO25469 AIF1L Knockout cell line (A549) Human AIF1L 1:3~1:4 Negative Online Inquiry

Background

AIF1L Gene Knockout Cell Lines represent a significant advancement in the field of genetic research, specifically designed to facilitate the study of the Apoptosis-Inducing Factor 1-Like (AIF1L) gene and its associated pathways. These cell lines contain targeted deletions of the AIF1L gene, allowing researchers to investigate the role of this gene in cellular processes such as apoptosis, mitochondrial function, and immune responses without the confounding effects of gene expression.

The mechanisms underlying the function of AIF1L are critical to understanding its contributions to various biological systems. By employing these knockout cell lines, scientists can elucidate the consequences of AIF1L deficiency on cell viability, cytokine production, and stress responses. This provides insights not only into basic biology but also into pathological states such as neurodegeneration and inflammation, where AIF1L is believed to have significant roles.

From a scientific standpoint, the importance of AIF1L Gene Knockout Cell Lines in both research and clinical settings cannot be overstated. They are invaluable for generating data that can lead to therapeutic strategies aimed at modulating AIF1L function in diseases like cancer and autoimmune disorders. Experimenting with these cell lines allows for a deeper understanding of the molecular mechanisms driving cellular responses, thus translating basic research into potential clinical applications.

This product's unique selling points include the high-quality standardization of the knockout methodology, which ensures reproducibility and reliability in experimental outcomes. Unlike traditional cell lines that express AIF1L, these knockout lines provide a clear and isolated model for studying gene function, making them essential tools in the arsenal of researchers focused on gene therapy, regenerative medicine, and pathophysiology.

For researchers and clinicians alike, the value of AIF1L Gene Knockout Cell Lines lies in their ability to streamline experimental design while providing robust models for the investigation of critical biological questions. With a commitment to excellence and extensive experience in biotechnological innovations, our company offers a wide range of genetic products designed to empower scientific discovery and drive forward the frontiers of biomedical research.

Please note that all services are for research use only. Not intended for any clinical use.

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