Gene: AHNAK
Official Full Name: AHNAK nucleoproteinprovided by HGNC
Gene Summary: The protein encoded by this gene is a large (700 kDa) structural scaffold protein consisting of a central domain with 128 aa repeats. The encoded protein may play a role in such diverse processes as blood-brain barrier formation, cell structure and migration, cardiac calcium channel regulation, and tumor metastasis. A much shorter variant encoding a 17 kDa isoform exists for this gene, and the shorter isoform initiates a feedback loop that regulates alternative splicing of this gene. [provided by RefSeq, Oct 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20541 | AHNAK Knockout cell line (HeLa) | Human | AHNAK | 1:3~1:6 | Negative | Online Inquiry |
KO20542 | AHNAK Knockout cell line (HCT 116) | Human | AHNAK | 1:2~1:4 | Negative | Online Inquiry |
KO20543 | AHNAK Knockout cell line (HEK293) | Human | AHNAK | 1:3~1:6 | Negative | Online Inquiry |
KO20544 | AHNAK Knockout cell line (A549) | Human | AHNAK | 1:3~1:4 | Negative | Online Inquiry |
AHNAK Gene Knockout Cell Lines are advanced research tools specifically engineered to facilitate the study of the AHNAK gene and its associated pathways. These cell lines have been constructed using CRISPR-Cas9 gene editing technology, providing a precise method for knocking out the AHNAK gene, which plays a critical role in various cellular processes, including cell adhesion, motility, and signaling. By creating a model where the AHNAK protein is absent, researchers can investigate its biological functions and contributions to cellular behavior in both physiological and pathological contexts.
The mechanisms underlying the function of AHNAK involve its interactions with cytoskeletal elements and various signaling proteins, making it integral to both cell structure and function. By utilizing these knockout cell lines, researchers can explore the implications of AHNAK loss in cancer progression, developmental biology, and neurobiology. This targeted approach not only enhances our understanding of AHNAK’s role but also contributes to broader knowledge regarding cell biology and gene regulation.
In comparison to traditional gene silencing methods, such as RNA interference, AHNAK Gene Knockout Cell Lines offer several advantages, including permanent gene modification and the ability to study long-term effects of gene deletion on cellular physiology. They enable high-throughput screening and the potential for application in drug discovery and therapeutic target validation, which are crucial in clinical settings.
The availability of these cell lines empowers researchers and clinicians alike, facilitating novel discoveries that could lead to the development of innovative treatments and therapeutic strategies. With a strong commitment to quality and scientific innovation, our company specializes in providing cutting-edge biological products like AHNAK Gene Knockout Cell Lines, ensuring that our customers have access to the best tools for their research endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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