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AGBL3 Knockout Cell Lines

Gene: AGBL3

Official Full Name: AGBL carboxypeptidase 3provided by HGNC

Gene Summary: Enables metallocarboxypeptidase activity. Involved in protein side chain deglutamylation. Predicted to be located in cytosol. Predicted to be active in centriole and cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO19947 AGBL3 Knockout cell line (HeLa) Human AGBL3 1:3~1:6 Negative Online Inquiry
KO19948 AGBL3 Knockout cell line (HCT 116) Human AGBL3 1:2~1:4 Negative Online Inquiry
KO19949 AGBL3 Knockout cell line (HEK293) Human AGBL3 1:3~1:6 Negative Online Inquiry
KO19950 AGBL3 Knockout cell line (A549) Human AGBL3 1:3~1:4 Negative Online Inquiry

Background

AGBL3 Gene Knockout Cell Lines are meticulously engineered cellular models that facilitate the investigation of the function of the AGBL3 gene through targeted gene knockout techniques. This innovative product comprises a collection of mammalian cell lines where the AGBL3 gene has been precisely disrupted, allowing researchers to explore the gene's role in various biological processes, including protein regulation, cell signaling, and metabolic pathways.

The primary mechanism by which these cell lines function involves the complete disruption of the AGBL3 gene through CRISPR-Cas9 gene editing or similar technologies. The resulting knockout creates a unique platform for studying the phenotypic and molecular changes that occur in the absence of AGBL3, providing insights into its involvement in diseases, particularly those related to cancer and neurodegeneration. Researchers can utilize these cell lines to perform assays that elucidate the gene's contributions to critical cellular functions and pathological mechanisms.

The scientific importance of AGBL3 Gene Knockout Cell Lines extends to both research and clinical applications. These cell lines serve as vital tools for the identification of potential therapeutic targets and biomarkers, enhancing drug discovery and development processes. Additionally, they can be used to validate findings from high-throughput screening efforts, thereby accelerating the translation of fundamental research into clinically relevant outcomes.

What sets AGBL3 Gene Knockout Cell Lines apart from conventional alternatives is their premade, ready-to-use nature, which significantly reduces the time and resources typically required for generating knockout models. By offering a highly specific and validated system, our product allows researchers to focus on their experimental goals rather than the challenges of gene editing.

For researchers and clinicians, the value of AGBL3 Gene Knockout Cell Lines lies in their ability to provide reproducible and reliable data, ensuring the accuracy and integrity of experimental outcomes. This product not only accelerates the pace of discovery but also enhances the potential for groundbreaking therapeutic advancements.

With a robust portfolio of biological products and a commitment to quality and innovation, our company stands at the forefront of scientific research solutions, empowering researchers to unlock new biological insights and develop next-generation therapeutics.

Please note that all services are for research use only. Not intended for any clinical use.

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