Home / AGBL2 Knockout Cell Lines

AGBL2 Knockout Cell Lines

Gene: AGBL2

Official Full Name: AGBL carboxypeptidase 2provided by HGNC

Gene Summary: Predicted to enable metallocarboxypeptidase activity and tubulin binding activity. Predicted to be involved in protein side chain deglutamylation. Located in centriole and ciliary basal body. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO19951 AGBL2 Knockout cell line (HeLa) Human AGBL2 1:3~1:6 Negative Online Inquiry
KO19952 AGBL2 Knockout cell line (A549) Human AGBL2 1:3~1:4 Negative Online Inquiry

Background

AGBL2 Gene Knockout Cell Lines are genetically engineered cellular models designed to specifically lack the expression of the AGBL2 gene, which encodes the cytosolic enzyme α-β hydrolase 2. These cell lines serve as invaluable tools for understanding the biological role of AGBL2 in various cellular processes, including microtubule dynamics, cell proliferation, and apoptosis. By utilizing CRISPR-Cas9 technology, AGBL2 knockout lines enable precise gene editing that allows researchers to elucidate the physiological and pathological functions associated with AGBL2 deficiency.

The primary mechanism through which these knockout lines operate is the disruption of AGBL2 function, enabling studies focused on the downstream effects related to cellular behavior and stress responses. Research has indicated that AGBL2 is implicated in a range of cellular processes, including modulation of the cellular cytoskeleton and regulation of mitotic progression. Understanding these mechanisms is critical, particularly in the context of cancer research and neurodegenerative diseases, where aberrations in cellular dynamics contribute to disease progression.

In research and clinical applications, AGBL2 Gene Knockout Cell Lines provide a unique platform for evaluating potential therapeutic targets and substances that might interact with AGBL2 or compensate for its loss. Compared to alternative models, these knockouts present a straightforward system for studying gene function without the confounding variables associated with partial loss of function models, such as knockdown studies or overexpression systems.

The unique selling points of AGBL2 knockout lines lie in their specificity, reliability, and ease of use. They allow for consistent and reproducible results across numerous experiments, which is essential for advancing our knowledge in both basic and applied biological sciences. As a product, these cell lines are essential for researchers and clinicians aiming to unlock novel therapeutic approaches and biomolecular interactions involving AGBL2.

Our company is committed to advancing scientific research by providing high-quality biological products tailored to the ongoing needs of the research community. With a focus on innovation and reliability, we strive to be the preferred source for researchers seeking dependable models to facilitate their groundbreaking work.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.