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AFTPH Knockout Cell Lines

Gene: AFTPH

Official Full Name: aftiphilinprovided by HGNC

Gene Summary: Enables clathrin binding activity. Predicted to be involved in intracellular transport. Located in Golgi apparatus; cytosol; and nucleoplasm. Part of AP-1 adaptor complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO19957 AFTPH Knockout cell line (HeLa) Human AFTPH 1:3~1:6 Negative Online Inquiry
KO19958 AFTPH Knockout cell line (HCT 116) Human AFTPH 1:2~1:4 Negative Online Inquiry
KO19959 AFTPH Knockout cell line (HEK293) Human AFTPH 1:3~1:6 Negative Online Inquiry
KO19960 AFTPH Knockout cell line (A549) Human AFTPH 1:3~1:4 Negative Online Inquiry

Background

AFTPH Gene Knockout Cell Lines are genetically engineered cell lines that have undergone targeted gene deletion of AFTPH, a gene implicated in various cellular processes, including transcriptional regulation and cellular metabolism. By creating a definitive AFTPH knockout model, researchers can delve into the gene’s functional implications and its role in cellular behavior, including growth, differentiation, and response to environmental cues.

The primary mechanism of AFTPH Gene Knockout Cell Lines involves CRISPR/Cas9 technology, allowing precise editing of the genomic sequence for the AFTPH gene. This method ensures effective disruption of the gene’s function, providing researchers with a powerful tool to study the downstream effects of its absence. The knockout cell lines exhibit altered phenotypic characteristics, making them invaluable for elucidating AFTPH’s physiological functions and pathway interactions in various biological contexts.

In both research and clinical settings, AFTPH knockout models are pivotal for validating hypotheses regarding gene function, drug screening, and biomarker discovery. The ability to study gene interactions in a controlled environment accelerates advances in fields such as cancer research, metabolic disorders, and developmental biology, offering insights that could lead to novel therapeutic approaches.

Compared to traditional knockout methods, AFTPH Gene Knockout Cell Lines offer a more reliable and reproducible solution, minimizing off-target effects and allowing for high-throughput screening capabilities. Their development streamlines experimental design and enhances data integrity, ultimately saving time and resources.

For researchers and clinicians striving to probe the complexities of cellular mechanisms, AFTPH Gene Knockout Cell Lines represent an essential addition to their experimental arsenal. By leveraging our commitment to scientific innovation and precise genetic engineering, our company provides top-tier products that enable groundbreaking discoveries in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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