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ADPRS Knockout Cell Lines

Gene: ADPRS

Official Full Name: ADP-ribosylserine hydrolaseprovided by HGNC

Gene Summary: This gene encodes a member of the ADP-ribosylglycohydrolase family. The encoded enzyme catalyzes the removal of ADP-ribose from ADP-ribosylated proteins. This enzyme localizes to the mitochondria, in addition to the nucleus and cytoplasm.[provided by RefSeq, Feb 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00061 ADPRS Knockout cell line (HCC1806) Human ADPRS 1:2~1:4 Negative Online Inquiry
KO19971 ADPRS Knockout cell line (HeLa) Human ADPRS 1:3~1:6 Negative Online Inquiry
KO19972 ADPRS Knockout cell line (HCT 116) Human ADPRS 1:2~1:4 Negative Online Inquiry
KO19973 ADPRS Knockout cell line (A549) Human ADPRS 1:3~1:4 Negative Online Inquiry

Background

ADPRS Gene Knockout Cell Lines are genetically engineered cellular models designed to facilitate the study of the ADPRS gene's function in both health and disease. These cell lines have undergone targeted gene editing, specifically using CRISPR/Cas9 technology, to create knockout variants that allow researchers to observe the effects of the absence of the ADPRS protein on cellular processes. By analyzing the resultant phenotype changes, researchers can elucidate the role of ADPRS in critical biological pathways, such as metabolic regulation and cell signaling.

The primary function of ADPRS Gene Knockout Cell Lines is to serve as a powerful tool for dissecting the molecular mechanisms underlying conditions associated with ADPRS dysregulation. This is particularly valuable in fields like cancer research and metabolic disorders, where understanding gene functionality can lead to novel therapeutic discoveries. These cell lines enable researchers to perform functional assays, drug screening, and gene interaction studies, providing insights that could drive innovation in targeted therapies.

Compared to alternative models, such as overexpression systems or non-specific loss-of-function approaches, ADPRS Gene Knockout Cell Lines offer a precise and reproducible method to investigate gene function without the confounding effects of background expression levels. Their specificity allows for clearer interpretation of experimental results, leading to more reliable data for clinical implications.

The value of ADPRS Gene Knockout Cell Lines is underscored by the potential to translate findings from bench to bedside, enhancing our understanding of disease mechanisms, guiding therapeutic interventions, and improving patient outcomes. Furthermore, researchers benefit from our commitment to providing high-quality, validated cell lines, ensuring reliable performance and reproducibility in experimental design.

With a strong background in molecular biology and genetics, our company prides itself on delivering innovative tools like the ADPRS Gene Knockout Cell Lines to advance scientific discovery and improve health care outcomes across diverse biological fields.

Please note that all services are for research use only. Not intended for any clinical use.

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