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ADGRF4 Knockout Cell Lines

Gene: ADGRF4

Official Full Name: adhesion G protein-coupled receptor F4provided by HGNC

Gene Summary: Sequence analysis of this gene suggests that it is encodes a member of the superfamily of G protein-couple receptors. G protein-coupled receptors typically contain seven hydrophobic transmembrane domains, interact with guanine nucleotide binding regulatory proteins, and detect molecules outside the cell and act to transduce these signals into intracellular responses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27511 ADGRF4 Knockout cell line (A549) Human ADGRF4 1:3~1:4 Negative Online Inquiry

Background

ADGRF4 Gene Knockout Cell Lines are specifically engineered cellular models that facilitate the study of the ADGRF4 gene, implicated in various physiological and pathological processes, including cellular signaling and adhesion. These knockout cell lines are created using advanced CRISPR-Cas9 technology, allowing researchers to precisely edit the genome and eliminate the expression of the ADGRF4 gene. This genetic modification enables scientists to explore the biological functions of ADGRF4, as well as its roles in health and disease.

The primary functionality of ADGRF4 Gene Knockout Cell Lines lies in their ability to provide a controlled environment to study the downstream effects of ADGRF4 absence. Researchers can analyze changes in cellular behavior, signaling pathways, and gene expression profiles, contributing to a deeper understanding of this receptor's role in various cellular contexts. These models are invaluable for investigating mechanisms underlying disorders such as cancer, cardiovascular diseases, and neurological disorders, as they shed light on the interactions and dependencies within cellular systems.

The scientific importance of ADGRF4 Gene Knockout Cell Lines is underscored by their versatility in both research and therapeutic potential. By providing a robust platform for drug screening, biomarker discovery, and genomics studies, they offer significant advantages over traditional cellular models, including enhanced specificity, reproducibility, and the ability to eliminate confounding variables linked to ADGRF4 expression.

Compared to alternatives, these knockout cell lines uniquely allow researchers to achieve a targeted approach in studying gene function without the complexities associated with transient knockdowns or less precise gene editing techniques. Their ease of use and compatibility with various assays make them an attractive option for both academic and pharmaceutical applications.

For researchers and clinicians, investing in ADGRF4 Gene Knockout Cell Lines means accessing cutting-edge tools that can accelerate discoveries and drive innovation in the understanding of complex biological systems. Our company, with its commitment to advancing genetic research tools, ensures that you receive high-quality, validated products that empower scientific exploration and contribute significantly to the field.

Please note that all services are for research use only. Not intended for any clinical use.

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