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ADD1 Knockout Cell Lines

Gene: ADD1

Official Full Name: adducin 1provided by HGNC

Gene Summary: Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, and gamma). Adducin acts as a heterodimer of the related alpha, beta, or gamma subunits. The protein encoded by this gene represents the alpha subunit. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. [provided by RefSeq, Aug 2017]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO01044 ADD1 Knockout cell line (HeLa) Human ADD1 1:3~1:6 Negative Online Inquiry
KO39110 ADD1 Knockout cell line (HCT 116) Human ADD1 1:2~1:4 Negative Online Inquiry
KO39111 ADD1 Knockout cell line (HEK293) Human ADD1 1:3~1:6 Negative Online Inquiry
KO39112 ADD1 Knockout cell line (A549) Human ADD1 1:3~1:4 Negative Online Inquiry

Background

ADD1 Gene Knockout Cell Lines are specialized cellular models developed to facilitate the study of the Adducin 1 (ADD1) gene's function and its implications in various biological processes. Gene knockout technology involves the targeted disruption of specific genes, allowing researchers to analyze the resultant phenotypic changes without the gene's normal expression. By generating these cell lines, scientists can investigate ADD1's role in cellular mechanisms such as cytoskeletal organization, ion transport, and cellular signaling, thereby understanding its contribution to physiological and pathological states.

The ADD1 gene is critical for maintaining membrane stability and regulating cell adhesion, and its knockout allows for an assessment of these cellular functions in a controlled environment. Researchers utilize these cell lines to elucidate the potential links between ADD1 dysregulation and diseases such as hypertension, diabetes, and neurological disorders, thus highlighting the gene's significance in both basic and applied biological research.

One of the key advantages of the ADD1 Gene Knockout Cell Lines is their specificity and reliability compared to other models, such as whole organisms or non-targeted cell line modifications. They offer a greater degree of control over experimental variables, allowing for more precise elucidation of gene function and mechanistic studies. Furthermore, these cell lines can be easily incorporated into high-throughput screening processes for drug discovery or therapeutic development.

For researchers and clinicians exploring the intricacies of gene function and its ramifications, the ADD1 Gene Knockout Cell Lines present a valuable tool that accelerates the discovery of novel insights into disease mechanisms and therapeutic interventions. Our company specializes in providing high-quality biological products and innovative solutions, ensuring that the ADD1 Gene Knockout Cell Lines meet the rigorous standards expected by the scientific community. We are committed to empowering researchers with reliable tools that advance the frontiers of biological research.

Please note that all services are for research use only. Not intended for any clinical use.

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