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ADCY7 Knockout Cell Lines

Gene: ADCY7

Official Full Name: adenylate cyclase 7provided by HGNC

Gene Summary: This gene encodes a membrane-bound adenylate cyclase that catalyses the formation of cyclic AMP from ATP and is inhibitable by calcium. The product of this gene is a member of the adenylyl cyclase class-4/guanylyl cyclase enzyme family that is characterized by the presence of twelve membrane-spanning domains in its sequences. Several transcript variants have been observed for this gene, but the full-length natures of only two have been determined so far. [provided by RefSeq, Oct 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO08800 ADCY7 Knockout cell line (HeLa) Human ADCY7 1:3~1:6 Negative Online Inquiry
KO08801 ADCY7 Knockout cell line (HCT 116) Human ADCY7 1:2~1:4 Negative Online Inquiry
KO08802 ADCY7 Knockout cell line (HEK293) Human ADCY7 1:3~1:6 Negative Online Inquiry
KO08803 ADCY7 Knockout cell line (A549) Human ADCY7 1:3~1:4 Negative Online Inquiry

Background

ADCY7 Gene Knockout Cell Lines are a pivotal tool in cellular and molecular biology research, designed to facilitate in-depth studies of the adenylyl cyclase 7 (ADCY7) gene’s function. These cell lines are genetically engineered to lack the functional ADCY7 protein, allowing scientists to investigate the physiological and pathological roles of ADCY7 in various biological processes. The primary mechanism of action lies in the disruption of cyclic AMP (cAMP) signaling pathways, critically important in modulating cellular responses to hormonal and neurotransmitters stimuli.

The scientific significance of ADCY7 Gene Knockout Cell Lines extends across numerous research domains, including neurobiology, cardiology, and endocrinology. By enabling researchers to elucidate the impacts of ADCY7 deficiency on cAMP-mediated effects, these cell lines serve as invaluable models for understanding conditions such as heart failure, mood disorders, and other conditions where cAMP signaling is altered. In clinical settings, they can contribute to drug discovery efforts by enabling a more targeted examination of therapeutic compounds that modulate cAMP levels.

Compared to traditional cell lines, ADCY7 Gene Knockout Cell Lines offer distinct advantages; their specificity allows for more accurate modeling of ADCY7-related pathways, thus enhancing the reliability and relevance of experimental data. This precision makes them an unparalleled choice for researchers seeking to establish causal relationships between ADCY7 and various biological outcomes.

For researchers and clinicians, the ability to manipulate specific genomic loci using knockout approaches represents a cutting-edge avenue for advancing biological insights and therapeutic strategies. Hence, the ADCY7 Gene Knockout Cell Lines not only enrich the repertoire of available research tools but also stand out due to their specificity and versatility.

Our company is recognized for its commitment to providing high-quality, scientifically validated biological products. With expertise in genetic engineering and cell line development, we ensure that our products meet rigorous standards to support groundbreaking research and innovation in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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