Gene: ADAMTSL4
Official Full Name: ADAMTS like 4provided by HGNC
Gene Summary: This gene is a member of ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs)-like gene family and encodes a protein with seven thrombospondin type 1 repeats. The thrombospondin type 1 repeat domain is found in many proteins with diverse biological functions including cellular adhesion, angiogenesis, and patterning of the developing nervous system. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Sep 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21669 | ADAMTSL4 Knockout cell line (HeLa) | Human | ADAMTSL4 | 1:3~1:6 | Negative | Online Inquiry |
KO21670 | ADAMTSL4 Knockout cell line (HCT 116) | Human | ADAMTSL4 | 1:2~1:4 | Negative | Online Inquiry |
KO21671 | ADAMTSL4 Knockout cell line (A549) | Human | ADAMTSL4 | 1:3~1:4 | Negative | Online Inquiry |
ADAMTSL4 Gene Knockout Cell Lines are advanced biological tools engineered to facilitate the study of the ADAMTSL4 gene's role in various physiological and pathological processes. This product features genetically modified cell lines in which the ADAMTSL4 gene has been inactivated, allowing researchers to investigate the functional consequences of its loss. ADAMTSL4 (A Disintegrin-like and Metalloproteinase with Thrombospondin Motifs-like 4) has been implicated in regulating cellular interactions and extracellular matrix organization, making these knockout lines essential for dissecting its contributions to tissue homeostasis and disease states.
The primary function of these cell lines lies in their ability to provide a controlled environment for detailed mechanistic studies. By observing changes in cellular behavior such as proliferation, migration, and differentiation in the absence of ADAMTSL4, researchers can uncover critical pathways influenced by this gene. This cellular model is invaluable for elucidating the molecular mechanisms underlying conditions such as cancer, fibrosis, and vascular diseases, making it a powerful tool in both basic and translational research.
The scientific importance of ADAMTSL4 Gene Knockout Cell Lines cannot be overstated, as they enable the exploration of gene function in conditions that are otherwise challenging to study. Their application spans a wide range of research areas, including gene therapy development, drug screening, and biomarker discovery, providing clinicians and researchers with insights that could lead to novel therapeutic strategies.
Compared to traditional gene knockdown methods, such as RNA interference, the ADAMTSL4 Gene Knockout Cell Lines offer a more stable and lasting means to investigate gene function. This is particularly valuable for long-term studies where consistent gene expression levels are crucial. Additionally, the specificity of knockout techniques minimizes off-target effects, resulting in more robust and reproducible experimental outcomes.
Researchers and clinicians will find ADAMTSL4 Gene Knockout Cell Lines to be a vital addition to their toolkit, as they not only streamline the process of studying gene function but also enhance the accuracy of experimental data. This product is essential for those looking to advance their understanding of ADAMTSL4-related mechanisms, ultimately aiding in the development of targeted therapeutics.
Our company specializes in providing high-quality, genetically engineered products designed to support innovative biomedical research. With a commitment to scientific excellence, we aim to empower researchers and clinicians with the tools they need to pursue their inquiries into gene function and disease mechanisms.
Please note that all services are for research use only. Not intended for any clinical use.
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