Gene: ADAM23
Official Full Name: ADAM metallopeptidase domain 23provided by HGNC
Gene Summary: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. It is reported that inactivation of this gene is associated with tumorigenesis in human cancers. [provided by RefSeq, May 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO33901 | ADAM23 Knockout cell line (HeLa) | Human | ADAM23 | 1:3~1:6 | Negative | Online Inquiry |
KO33902 | ADAM23 Knockout cell line (HEK293) | Human | ADAM23 | 1:3~1:6 | Negative | Online Inquiry |
KO33903 | ADAM23 Knockout cell line (A549) | Human | ADAM23 | 1:3~1:4 | Negative | Online Inquiry |
ADAM23 Gene Knockout Cell Lines are specially engineered cellular models that facilitate the study of the ADAM23 gene's function through targeted gene disruption. ADAM23, an a disintegrin and metalloproteinase, is involved in various processes, including cell adhesion, migration, and signaling, and plays a critical role in the regulation of the immune response and neural development. By utilizing CRISPR-Cas9 or similar gene-editing techniques, these knockout cell lines provide researchers with a powerful tool to investigate the biological role of ADAM23, particularly in the context of cancer, autoimmune diseases, and neurodegenerative disorders.
The primary mechanism through which these cell lines operate is by abolishing the expression of the ADAM23 protein, allowing scientists to assess the resultant phenotypic changes. This enables a deeper understanding of ADAM23's contributions to diverse biological processes and disease mechanisms. With the growing significance of ADAM proteins in therapeutic research and development, these knockout cell lines also provide a platform for drug discovery and biomarker identification, making them invaluable in both preclinical and clinical settings.
One significant advantage of the ADAM23 Gene Knockout Cell Lines is their ability to closely mimic the physiological conditions of human cells, offering an accurate representation for experimental outcomes. This contrasts with standard cell lines that may not express ADAM23 effectively. Furthermore, the ease of use of these cell lines, combined with robust protocols for maintenance and usage, allows for streamlined integration into various research workflows.
For researchers, clinicians, and pharmaceutical companies, the value of ADAM23 Gene Knockout Cell Lines lies in their potential to accelerate the understanding of critical pathways and mechanisms associated with multiple diseases. As such, these tools are essential for innovative research that could lead to novel therapeutic approaches.
Our company, with a strong commitment to advancing biological research, specializes in providing high-quality genetic models that empower the scientific community. By focusing on precision and reproducibility, we ensure that our products, including the ADAM23 Gene Knockout Cell Lines, meet the highest standards of research excellence.
Please note that all services are for research use only. Not intended for any clinical use.
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