Gene: ACY3
Official Full Name: aminoacylase 3provided by HGNC
Gene Summary: Predicted to enable aminoacylase activity. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO02980 | ACY3 Knockout cell line (A549) | Human | ACY3 | 1:3~1:4 | Negative | Online Inquiry |
ACY3 Gene Knockout Cell Lines are genetically modified cell lines in which the acylase 3 (ACY3) gene has been rendered inoperative or "knocked out." This manipulation is achieved through advanced gene-editing techniques, typically CRISPR-Cas9 or RNA interference, allowing researchers to study the functional consequences of ACY3 deficiency. The ACY3 protein plays a crucial role in the hydrolysis of N-acyl amino acids, impacting various physiological processes including metabolic regulation and signal transduction pathways.
The primary function of these knockout cell lines is to serve as invaluable tools for investigating the biological roles of ACY3 in different cellular contexts. By observing the phenotypic and molecular changes in these cell lines, researchers can elucidate the pathways and mechanisms through which ACY3 influences cell behavior. This contributes significantly to our understanding of metabolic disorders and their potential therapeutic targets.
In a research or clinical setting, ACY3 Gene Knockout Cell Lines hold promise for studying diseases associated with dysregulated lipid metabolism and inflammatory responses. Additionally, they offer a platform for drug discovery and validation, enhancing the process of identifying compounds that can modulate ACY3 activity.
Compared to alternative models, such as traditional wild-type cell lines or conventional knockout organisms, ACY3 Gene Knockout Cell Lines provide a more controlled environment for studying gene function. They allow for more precise manipulation and characterization of ACY3's role, enabling faster and more reliable results in experimental assays.
The value of ACY3 Gene Knockout Cell Lines extends beyond academic research; they are essential for pharmaceutical companies working to develop targeted therapies and diagnostics. Our commitment to using cutting-edge gene-editing technologies ensures that these cell lines are rigorously tested for quality and functionality.
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