Gene: ACTR5
Official Full Name: actin related protein 5provided by HGNC
Gene Summary: Involved in several processes, including DNA repair; chromatin remodeling; and regulation of nucleobase-containing compound metabolic process. Located in cytoplasm and nucleus. Part of Ino80 complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO22108 | ACTR5 Knockout cell line (HeLa) | Human | ACTR5 | 1:3~1:6 | Negative | Online Inquiry |
KO22109 | ACTR5 Knockout cell line (HCT 116) | Human | ACTR5 | 1:2~1:4 | Negative | Online Inquiry |
KO22110 | ACTR5 Knockout cell line (HEK293) | Human | ACTR5 | 1:3~1:6 | Negative | Online Inquiry |
KO22111 | ACTR5 Knockout cell line (A549) | Human | ACTR5 | 1:3~1:4 | Negative | Online Inquiry |
ACTR5 Gene Knockout Cell Lines are specialized cellular models designed to facilitate the functional analysis of the ACTR5 gene, which encodes a component critical for cellular transport processes and cytoskeletal dynamics. These knockout cell lines are generated through precise genetic engineering techniques, such as CRISPR-Cas9, enabling the complete ablation of the ACTR5 gene, thereby allowing researchers to study the gene's role in various biological processes, including cell division, migration, and intracellular trafficking.
The primary function of ACTR5 is to serve as part of the Arp2/3 complex, which is pivotal for actin polymerization and the formation of branched actin networks. By knocking out ACTR5, researchers can elucidate its essential contributions to cellular architecture and motility, helping to decode the intricacies of cellular behavior in health and disease. The availability of these cell lines empowers scientists to explore the implications of ACTR5 deficiency on tumor metastasis, developmental biology, and neurodegeneration.
Scientific importance lies in the ability of ACTR5 knockout cell lines to model diseases that arise from cytoskeletal dysfunction, offering insights critical for drug discovery and therapeutic interventions. These models are particularly valuable in translational research, providing evidence for the development of targeted therapies that can circumvent the effects of ACTR5-related pathway disruptions.
Compared to traditional cell lines or chemical inhibitors, ACTR5 knockout cell lines offer a unique and precise approach. Researchers benefit from the genetic authenticity these models provide, enabling a more thorough understanding of gene function and interaction without the artifacts associated with pharmacological manipulation.
For researchers and clinicians alike, ACTR5 Gene Knockout Cell Lines represent a powerful tool for unraveling the complexities of gene function in cellular processes. With a commitment to advancing research methodologies, our company specializes in delivering high-quality genetic models designed to propel your research forward and foster innovative discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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