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ACSF3 Knockout Cell Lines

Gene: ACSF3

Official Full Name: acyl-CoA synthetase family member 3provided by HGNC

Gene Summary: This gene encodes a member of the acyl-CoA synthetase family of enzymes that activate fatty acids by catalyzing the formation of a thioester linkage between fatty acids and coenzyme A. The encoded protein is localized to mitochondria, has high specificity for malonate and methylmalonate and possesses malonyl-CoA synthetase activity. Mutations in this gene are a cause of combined malonic and methylmalonic aciduria. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Sep 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00804 ACSF3 Knockout cell line(AGS) Human ACSF3 1:2~1:4 Negative Online Inquiry
KO20039 ACSF3 Knockout cell line (HeLa) Human ACSF3 1:3~1:6 Negative Online Inquiry
KO20040 ACSF3 Knockout cell line (HCT 116) Human ACSF3 1:2~1:4 Negative Online Inquiry
KO20041 ACSF3 Knockout cell line (HEK293) Human ACSF3 1:3~1:6 Negative Online Inquiry
KO20042 ACSF3 Knockout cell line (A549) Human ACSF3 1:3~1:4 Negative Online Inquiry

Background

ACSF3 Gene Knockout Cell Lines represent a cutting-edge tool in genetic research and therapeutic development, designed specifically to facilitate the investigation of the ACSF3 gene's functions. These cell lines are genetically engineered to lack functional components of the ACSF3 gene, enabling researchers to dissect its role in metabolic processes and cellular signaling pathways. The removal of this gene allows for the observation of phenotypic changes, biochemical alterations, and various cellular responses that may elucidate its relevance in health and disease.

The primary function of ACSF3 Gene Knockout Cell Lines lies in their ability to create a cellular environment devoid of ACSF3 activity, which is essential for studying its role in cellular metabolism and potential implications in diseases like cancer and metabolic disorders. The mechanism underlying their application involves CRISPR-Cas9 technology, enabling precise edits to the genome that result in targeted gene disruption. This ensures reproducibility and reliability in experimental results, as researchers can replicate the knockout effect in different studies.

From a scientific standpoint, these cell lines are invaluable in a range of applications including drug discovery, disease modeling, and functional genomics. They allow for the identification of downstream effects of the ACSF3 gene, providing insights that can guide the development of novel therapeutic strategies. Moreover, their ability to serve as control models in comparative studies enhances the robustness of experimental findings.

One of the key advantages of ACSF3 Gene Knockout Cell Lines is their specificity and high fidelity in mimicking genetic conditions related to ACSF3 dysfunction, setting them apart from traditional cell lines and models that may carry confounding factors. This product offers a unique selling point by ensuring consistent results in a customizable platform suited to various experimental designs, significantly accelerating the research timeline.

For researchers and clinicians, the value of ACSF3 Gene Knockout Cell Lines lies in their potential to pave the way for groundbreaking discoveries that may alter the landscape of precision medicine. By utilizing these specialized cell lines, users can gain a clearer understanding of biological mechanisms and contribute to the development of targeted therapies.

Our company prides itself on a strong commitment to providing high-quality biological products, backed by rigorous scientific validation and a team of experts dedicated to advancing research and clinical applications. With ACSF3 Gene Knockout Cell Lines, we aim to empower scientists in their quest for innovative solutions and transformative insights.

Please note that all services are for research use only. Not intended for any clinical use.

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