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ACOT9 Knockout Cell Lines

Gene: ACOT9

Official Full Name: acyl-CoA thioesterase 9provided by HGNC

Gene Summary: The protein encoded by this gene is a mitochondrial acyl-CoA thioesterase of unknown function. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29088 ACOT9 Knockout cell line (HeLa) Human ACOT9 1:3~1:6 Negative Online Inquiry
KO29089 ACOT9 Knockout cell line (HCT 116) Human ACOT9 1:2~1:4 Negative Online Inquiry
KO29090 ACOT9 Knockout cell line (HEK293) Human ACOT9 1:3~1:6 Negative Online Inquiry
KO29091 ACOT9 Knockout cell line (A549) Human ACOT9 1:3~1:4 Negative Online Inquiry

Background

ACOT9 Gene Knockout Cell Lines are advanced cellular models engineered to lack the ACOT9 gene, which encodes for acyl-CoA thioesterases. This enzyme plays a crucial role in fatty acid metabolism by regulating the levels of acyl-CoA thioesters, thereby influencing lipid homeostasis and energy metabolism within cells. By eliminating the ACOT9 gene, researchers can investigate the biochemical pathways and physiological consequences associated with disrupted fatty acid metabolism, thus providing insight into various metabolic disorders and diseases, including obesity and diabetes.

The key functions of ACOT9 Gene Knockout Cell Lines include the elucidation of metabolic pathways mediated by fatty acids, the exploration of lipid signaling mechanisms, and the assessment of cellular responses to changes in lipid levels. This is achieved through various experimental approaches such as gene expression assays, metabolic profiling, and cellular signaling studies that can reveal how the absence of ACOT9 alters cellular behavior.

Scientifically, these cell lines hold significant importance in both basic and applied research. They serve as vital tools for understanding the role of lipid metabolism in human health and disease contexts. Moreover, ACOT9 knockout models can be utilized to screen potential therapeutic agents aimed at modulating lipid metabolism, offering valuable insights for pharmaceutical development.

One of the unique selling points of ACOT9 Gene Knockout Cell Lines is their specificity and tailored application in studying fatty acid-related metabolic pathways, which may not be effectively addressed with wild-type models or less specific genetic modifications. Additionally, these cell lines are rigorously validated for consistent performance and reproducibility, ensuring reliability in experimental results.

For researchers and clinicians, the ability to dissect the function of ACOT9 within lipid metabolism provides an unparalleled opportunity to identify novel biomarkers or therapeutic targets. By integrating genomic, proteomic, and metabolomic analyses, users can derive comprehensive insights that could pave the way for innovative strategies in metabolic disease management.

Our company has a longstanding commitment to advancing biomedical research through the development of high-quality biological products. With expertise in genetic engineering and cellular biology, we provide comprehensive support to researchers in their quest to unlock the complexities of human health and disease, making our ACOT9 Gene Knockout Cell Lines an essential resource for groundbreaking research.

Please note that all services are for research use only. Not intended for any clinical use.

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