Gene: ACAP1
Official Full Name: ArfGAP with coiled-coil, ankyrin repeat and PH domains 1provided by HGNC
Gene Summary: Predicted to enable GTPase activator activity and metal ion binding activity. Predicted to be involved in protein transport. Located in membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO32833 | ACAP1 Knockout cell line (HeLa) | Human | ACAP1 | 1:3~1:6 | Negative | Online Inquiry |
KO32834 | ACAP1 Knockout cell line (HCT 116) | Human | ACAP1 | 1:2~1:4 | Negative | Online Inquiry |
KO32835 | ACAP1 Knockout cell line (A549) | Human | ACAP1 | 1:3~1:4 | Negative | Online Inquiry |
ACAP1 Gene Knockout Cell Lines are genetically modified cell lines specifically engineered to lack the Anterior Calmodulin-binding Protein 1 (ACAP1) gene. This targeted knockout enables researchers to investigate the roles and pathways associated with ACAP1 impairments in cellular processes such as vesicle trafficking, intracellular signaling, and membrane dynamics. These cell lines serve as powerful tools for dissecting the molecular mechanisms underlying various physiological and pathological conditions.
The functional mechanics of ACAP1 involve its crucial participation in the endocytic pathway, primarily by regulating clathrin-mediated endocytosis. By utilizing these knockout cell lines, researchers can elucidate the contributions of ACAP1 to receptor regulation and membrane recycling, providing insights into how dysregulation may lead to diseases such as cancer or neurodegenerative disorders. This makes ACAP1 Gene Knockout Cell Lines particularly valuable in basic research and therapeutic development.
In a clinical or research setting, employing ACAP1 knockout lines equips scientists with the ability to model disease states more accurately and test potential interventions. Compared to traditional tissue culture models, these knockout cell lines offer specificity in targeting genetic pathways, leading to more reproducible and relevant data, thereby accelerating the translational research process.
The primary advantage of using ACAP1 Gene Knockout Cell Lines lies in their customization and adaptability for various experimental applications, such as high-throughput screening or gene editing investigations. They provide a unique selling proposition by allowing for the elucidation of ACAP1 functions with clarity, thus filling critical knowledge gaps in the field.
For researchers and clinicians aiming to explore novel therapeutic avenues or investigate cellular mechanisms, ACAP1 Gene Knockout Cell Lines offer the precision and reliability necessary to drive innovation. By utilizing our expertise in the development and validation of specialized genetic models, we ensure that our products are of the highest quality, bolstering your research efforts and ultimately contributing to advancements in the field.
Please note that all services are for research use only. Not intended for any clinical use.
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