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ACAA2 Knockout Cell Lines

Gene: ACAA2

Official Full Name: acetyl-CoA acyltransferase 2provided by HGNC

Gene Summary: The encoded protein catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO31853 ACAA2 Knockout cell line (HeLa) Human ACAA2 1:3~1:6 Negative Online Inquiry
KO31854 ACAA2 Knockout cell line (HCT 116) Human ACAA2 1:2~1:4 Negative Online Inquiry
KO31855 ACAA2 Knockout cell line (HEK293) Human ACAA2 1:3~1:6 Negative Online Inquiry
KO31856 ACAA2 Knockout cell line (A549) Human ACAA2 1:3~1:4 Negative Online Inquiry

Background

ACAA2 Gene Knockout Cell Lines are specialized cell models designed to facilitate the study of the Acetyl-CoA Acyltransferase 2 (ACAA2) gene's function by effectively disrupting its expression. These cell lines are engineered using advanced CRISPR/Cas9 gene-editing technology, creating a targeted knockout of the ACAA2 gene, which plays a pivotal role in the metabolic processing of fatty acids and in the cellular response to metabolic stress.

The primary function of these cell lines lies in enabling researchers to investigate the metabolic pathways linked to ACAA2, particularly focusing on its involvement in β-oxidation and lipid metabolism. By comparing the knockout cells to wild-type counterparts, scientists can elucidate the gene's contributions to metabolic disorders and cancer biology, providing valuable insights into therapeutic targets for conditions such as obesity and type 2 diabetes.

The scientific importance of ACAA2 Gene Knockout Cell Lines extends into both research and clinical applications. They serve as crucial tools for drug discovery and development, enabling researchers to screen for compounds that can modulate lipid metabolism. Additionally, they aid in the study of genetic factors that contribute to diseases associated with dysregulated fatty acid oxidation.

What sets our ACAA2 Gene Knockout Cell Lines apart from alternatives is their validated performance and reliability. Each line undergoes rigorous quality control, ensuring the complete knockout of the ACAA2 gene and maintaining stability across passages. This provides researchers with confidence in reproducibility and data integrity.

For researchers and clinicians focused on metabolic research or therapeutic development, these cell lines are invaluable assets that can catalyze discoveries leading to significant advancements in understanding human health and disease. Trust in our company's expertise in producing high-quality biological products, underpinned by a commitment to scientific excellence, ensures that you receive reliable tools essential for groundbreaking research.

Please note that all services are for research use only. Not intended for any clinical use.

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