Home / ABLIM3 Knockout Cell Lines

ABLIM3 Knockout Cell Lines

Gene: ABLIM3

Official Full Name: actin binding LIM protein family member 3provided by HGNC

Gene Summary: This gene encodes a member of the actin-binding LIM (abLIM) family of proteins. These proteins are characterized by an N-terminal LIM domain and a C-terminal dematin-like domain. The encoded protein interacts with actin filaments and may be a component of adherens junctions in several cell types. A variant of this gene may be associated with pain sensitivity in male human patients. [provided by RefSeq, Sep 2016]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30205 ABLIM3 Knockout cell line (HeLa) Human ABLIM3 1:3~1:6 Negative Online Inquiry
KO30206 ABLIM3 Knockout cell line (HCT 116) Human ABLIM3 1:2~1:4 Negative Online Inquiry
KO30207 ABLIM3 Knockout cell line (A549) Human ABLIM3 1:3~1:4 Negative Online Inquiry

Background

ABLIM3 Gene Knockout Cell Lines are advanced cellular models engineered for the targeted disruption of the ABLIM3 gene, a crucial player in various cellular processes, including cytoskeletal dynamics and cellular signal transduction. These cell lines are meticulously created using CRISPR-Cas9 gene-editing technology, allowing for precise and efficient gene knockout, which elucidates the functional role of ABLIM3 and its implications in health and disease.

The primary mechanism through which these cell lines function involves the complete ablation of ABLIM3 expression, which permits researchers to investigate the consequences of this gene's loss in vitro. This allows for the elucidation of pathways involved in cell migration, proliferation, and apoptosis, broadened by the intricate interplay of cytoskeletal structures and signaling cascades. The ABLIM3 knockout model is of immense scientific importance, facilitating studies on its role in cancer biology, neurodegenerative disorders, and other pathologies where cellular architecture and signaling are disrupted.

What sets ABLIM3 Gene Knockout Cell Lines apart from alternative models is the high specificity and efficiency associated with their creation. Many conventional models may rely on less precise gene disruption techniques, leading to off-target effects and variable outcomes. In contrast, the use of CRISPR-Cas9 ensures that ABLIM3 is effectively and reliably knocked out, providing cleaner data for researchers seeking to understand its biological functions.

These cell lines offer unparalleled value to researchers and clinicians, as they enable new insights into the potential therapeutic implications of modulating ABLIM3 activity. For studies focused on drug development, personalized medicine, and tailored therapeutic approaches, these models provide an essential platform for hypothesis testing and validation.

Our company is renowned for producing high-quality biological products backed by a commitment to scientific excellence and innovation. With expertise in creating precise and reliable cellular models, we are dedicated to advancing research in molecular biology and genetics, ensuring that our customers have access to the tools necessary for groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.