Gene: ABLIM1
Official Full Name: actin binding LIM protein 1provided by HGNC
Gene Summary: This gene encodes a LIM zinc-binding domain-containing protein that binds to actin filaments and mediates interactions between actin and cytoplasmic targets. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO36805 | ABLIM1 Knockout cell line (HeLa) | Human | ABLIM1 | 1:3~1:6 | Negative | Online Inquiry |
KO36806 | ABLIM1 Knockout cell line (HCT 116) | Human | ABLIM1 | 1:2~1:4 | Negative | Online Inquiry |
KO36807 | ABLIM1 Knockout cell line (HEK293) | Human | ABLIM1 | 1:3~1:6 | Negative | Online Inquiry |
KO36808 | ABLIM1 Knockout cell line (A549) | Human | ABLIM1 | 1:3~1:4 | Negative | Online Inquiry |
ABLIM1 Gene Knockout Cell Lines are genetically modified cell lines in which the ABLIM1 gene has been silenced or deleted, resulting in a powerful tool for studying the biological functions and mechanisms of this critical protein. ABLIM1 (Actin Binding LIM Protein 1) plays a significant role in cellular processes such as cytoskeletal organization, cell migration, and signal transduction. By utilizing these knockout cell lines, researchers can investigate the specific contributions of ABLIM1 to various cellular pathways and its implications in diseases, including cancer and neurodegenerative disorders.
The key mechanism behind ABLIM1 knockout is the use of CRISPR-Cas9 gene-editing technology, which allows for precise modifications to the genomic DNA. This targeted approach not only ensures the reliable ablation of the ABLIM1 gene but also minimizes off-target effects that could confound results. By incorporating these knockout cell lines into experimental designs, researchers can uncover novel insights into the functional attributes of ABLIM1, including its interactions with other cytoskeletal proteins and its involvement in cellular signaling pathways.
In research and clinical settings, ABLIM1 Gene Knockout Cell Lines are invaluable for elucidating the roles of ABLIM1 in cellular processes and disease mechanisms. These cell lines offer significant advantages over traditional methods, such as whole-animal models, by providing a controlled in vitro environment that is conducive to high-throughput screening, gene expression analysis, and therapeutic discovery. This specificity allows for more streamlined experimental designs, reducing time and costs associated with drug development.
Researchers, clinicians, and biopharmaceutical companies can greatly benefit from the insights gained using ABLIM1 genotype models, positioning them for breakthroughs in understanding disease pathways, drug interaction mechanisms, and potential therapeutic targets. Each line is rigorously characterized and validated, guaranteeing reproducibility and reliability in experimental applications.
Our company, renowned for its cutting-edge biotechnological innovations, specializes in providing high-quality gene-editing tools and cellular models. We leverage our expertise to ensure that products like the ABLIM1 Gene Knockout Cell Lines empower the scientific community to advance their research and translate their findings into real-world therapies.
Please note that all services are for research use only. Not intended for any clinical use.
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