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ABHD6 Knockout Cell Lines

Gene: ABHD6

Official Full Name: abhydrolase domain containing 6, acylglycerol lipaseprovided by HGNC

Gene Summary: Enables monoacylglycerol lipase activity. Involved in acylglycerol catabolic process. Predicted to be located in late endosome membrane and lysosomal membrane. Predicted to be part of AMPA glutamate receptor complex. Predicted to be active in GABA-ergic synapse; glutamatergic synapse; and postsynaptic membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO06498 ABHD6 Knockout cell line (HeLa) Human ABHD6 1:3~1:6 Negative Online Inquiry
KO06499 ABHD6 Knockout cell line (HCT 116) Human ABHD6 1:2~1:4 Negative Online Inquiry
KO06500 ABHD6 Knockout cell line (HEK293) Human ABHD6 1:3~1:6 Negative Online Inquiry
KO06501 ABHD6 Knockout cell line (A549) Human ABHD6 1:3~1:4 Negative Online Inquiry

Background

ABHD6 Gene Knockout Cell Lines are genetically modified cell lines tailored to specifically lack the expression of the Abhd6 gene, which encodes for the alpha/beta hydrolase domain-containing protein 6. This product is essential for researchers investigating the physiological and pathological roles of the ABHD6 enzyme in lipid metabolism, neurobiology, and various disease models, particularly in the context of neurodegenerative disorders.

The primary function of these knockout cell lines is to facilitate studies on the mechanistic pathways influenced by ABHD6. By eliminating this specific gene, researchers can observe downstream effects on lipid signaling, endocannabinoid metabolism, and other metabolic processes. The resulting cellular responses allow for a deeper understanding of the gene’s role, enabling studies that investigate its implications in diseases such as multiple sclerosis, schizophrenia, and inflammation-related conditions.

The scientific significance of ABHD6 Gene Knockout Cell Lines lies in their application across basic and translational research. They serve as a powerful tool for exploring gene function, validating drug targets, and elucidating metabolic pathways, thereby driving innovation in therapeutic developments. Furthermore, their utility in high-throughput screening assays positions them as vital assets in the pharmaceutical industry.

Compared to alternative models, ABHD6 Gene Knockout Cell Lines provide specificity and reproducibility that are often lacking in more generalized models. Their adaptability in various cellular environments enhances their application scope, making them suitable for diverse types of studies and experimental designs.

For researchers and clinicians dedicated to advancing biomedical science, the value of ABHD6 Gene Knockout Cell Lines is profound. These cell lines not only bridge the gap between basic research and clinical applications but also empower scientists to discover novel insights that could lead to innovative therapeutic strategies.

Our company is renowned for its commitment to quality and precision in biological products, backed by extensive expertise in gene editing technologies. We pride ourselves on providing tools that enhance research capabilities and contribute substantially to scientific advancement.

Please note that all services are for research use only. Not intended for any clinical use.

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