Gene: ABHD16A
Official Full Name: abhydrolase domain containing 16A, phospholipaseprovided by HGNC
Gene Summary: A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for tumor necrosis factor alpha and tumor necrosis factor beta. These genes are all within the human major histocompatibility complex class III region. The protein encoded by this gene is thought to be involved in some aspects of immunity. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34395 | ABHD16A Knockout cell line (HeLa) | Human | ABHD16A | 1:3~1:6 | Negative | Online Inquiry |
KO34396 | ABHD16A Knockout cell line (HCT 116) | Human | ABHD16A | 1:2~1:4 | Negative | Online Inquiry |
KO34397 | ABHD16A Knockout cell line (HEK293) | Human | ABHD16A | 1:3~1:6 | Negative | Online Inquiry |
KO34398 | ABHD16A Knockout cell line (A549) | Human | ABHD16A | 1:3~1:4 | Negative | Online Inquiry |
ABHD16A Gene Knockout Cell Lines are specifically engineered cellular models designed to enable comprehensive studies of the ABHD16A gene's biological functions and associated pathways. This product entails the knockout of the ABHD16A gene, a significant enzyme implicated in lysophospholipid metabolism and cellular signaling processes. By truncating this gene, researchers can effectively analyze the downstream effects of its absence, facilitating an understanding of its role in lipid metabolism, neurobiology, and potential implications in various disorders such as neurodegenerative diseases.
The key functionality of these knockout cell lines stems from their ability to mimic disease models, thereby allowing for the exploration of the mechanistic underpinnings of conditions associated with ABHD16A dysregulation. By studying these modified cells, researchers can elucidate changes in cellular behavior, including alterations in lipid profiles, cell proliferation, and apoptosis pathways. This detailed understanding fosters the discovery of new therapeutic targets and biomarkers, essential for advancing biomedical research.
The scientific importance of ABHD16A Gene Knockout Cell Lines extends to multiple applications in both academic and pharmaceutical research settings. These cell lines support high-throughput screening for potential therapeutic compounds and are pivotal in drug development phases targeting lipid metabolic disorders. Furthermore, the use of these models ensures reproducibility and precision in experiments, which are critical for obtaining reliable data.
Compared to traditional cell models, our ABHD16A knockout lines offer unique advantages, including superior specificity for ABHD16A-related studies, ease of use, and enhanced performance in complex lipid assays. This specificity significantly reduces confounding variables, providing clearer insights into the role of ABHD16A.
Researchers and clinicians will find immense value in these cell lines, as they can help streamline research methodologies, drive innovations in therapeutic approaches, and ultimately contribute to the advancement of human health. Our company brings years of expertise in genetic engineering and cell line development, ensuring that our products meet the highest standards of quality and reliability while driving forward cutting-edge research.
Please note that all services are for research use only. Not intended for any clinical use.
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