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ABHD15 Knockout Cell Lines

Gene: ABHD15

Official Full Name: abhydrolase domain containing 15provided by HGNC

Gene Summary: Predicted to enable monoacylglycerol lipase activity and short-chain carboxylesterase activity. Predicted to be involved in adipose tissue development and lipid catabolic process. Located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30538 ABHD15 Knockout cell line (HeLa) Human ABHD15 1:3~1:6 Negative Online Inquiry
KO30539 ABHD15 Knockout cell line (HCT 116) Human ABHD15 1:2~1:4 Negative Online Inquiry
KO30540 ABHD15 Knockout cell line (HEK293) Human ABHD15 1:3~1:6 Negative Online Inquiry
KO30541 ABHD15 Knockout cell line (A549) Human ABHD15 1:3~1:4 Negative Online Inquiry

Background

ABHD15 Gene Knockout Cell Lines represent a vital tool in the exploration of cellular mechanisms and disease modeling. These specialized cell lines have been genetically engineered to disable the function of the Abhydrolase Domain Containing 15 gene, which is known to play a significant role in lipid metabolism and cellular signaling pathways. By successfully knocking out this gene, researchers can investigate the diverse biological implications of ABHD15 deficiency, providing deeper insights into metabolic disorders and neurodegenerative diseases linked to lipid dysregulation.

The primary function of the ABHD15 Gene Knockout Cell Lines lies in their ability to serve as a model for studying the consequences of impaired lipid homeostasis. Through loss-of-function assays, researchers can examine alterations in metabolic pathways, cellular proliferation, and mechanistic dysfunctions that may contribute to disease progression. This product enables detailed exploration of the protein's interactions and its role in the endocannabinoid system, which is crucial for understanding conditions such as anxiety, pain, and inflammation.

From a scientific perspective, the applications of ABHD15 Gene Knockout Cell Lines are extensive. In research laboratories, these cell lines provide an essential tool for drug discovery, allowing for the screening of potential therapeutic agents that target lipid pathways. Clinically, the insights gained from these models can lead to novel approaches for treating diseases related to lipid metabolism, including obesity and diabetes.

What sets the ABHD15 Gene Knockout Cell Lines apart from alternative models is their precise genetic modification and the reliability of repeatibility in scientific outcomes. Unlike generalized cell line models, these knockout lines offer targeted insights with controlled variables, ensuring that the data obtained is both rigorous and reproducible.

For researchers and clinicians dedicated to advancing the understanding of metabolic disorders, ABHD15 Gene Knockout Cell Lines offer undeniable value. They provide a unique opportunity to dissect complex biological systems and facilitate the journey from discovery to application in therapeutic settings. Our company is committed to supporting the scientific community with high-quality, innovative research tools that enhance experimental robustness and drive forward medical advancements.

Please note that all services are for research use only. Not intended for any clinical use.

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