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ABCF3 Knockout Cell Lines

Gene: ABCF3

Official Full Name: ATP binding cassette subfamily F member 3provided by HGNC

Gene Summary: This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ATP-binding cassette proteins transport various molecules across extra- and intracellular membranes. The protein encoded by this gene displays antiviral effect against flaviviruses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2017]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29296 ABCF3 Knockout cell line (HeLa) Human ABCF3 1:3~1:6 Negative Online Inquiry
KO29297 ABCF3 Knockout cell line (HCT 116) Human ABCF3 1:2~1:4 Negative Online Inquiry
KO29298 ABCF3 Knockout cell line (HEK293) Human ABCF3 1:3~1:6 Negative Online Inquiry
KO29299 ABCF3 Knockout cell line (A549) Human ABCF3 1:3~1:4 Negative Online Inquiry

Background

ABCF3 Gene Knockout Cell Lines are genetically engineered cellular models designed to specifically lack the expression of the ABCF3 gene, a member of the ATP-binding cassette (ABC) transporter superfamily. These cell lines serve as invaluable tools for investigating the functional role of the ABCF3 protein in various biological processes, including drug metabolism, cell signaling, and resistance mechanisms in cancer.

The key function of the ABCF3 gene knockout is to facilitate the study of gene and protein interactions in cellular environments devoid of ABCF3 activity. Researchers employ CRISPR-Cas9 technology to create precise deletions in the ABCF3 gene, thereby producing a stable and reproducible model. This gene knockout offers insights into the molecular pathways affected by ABCF3, enabling investigations into how its absence impacts cellular responses to pharmaceuticals and cellular stressors.

Scientifically, ABCF3 Gene Knockout Cell Lines play a pivotal role in research areas such as pharmacogenomics, cancer biology, and cellular physiology. They allow for the assessment of drug efficacy, the exploration of potential therapeutic targets, and the understanding of resistance mechanisms in diseases where ABC transporters are implicated. Their applications extend to academia and the biotechnology industry, where they are instrumental in developing new therapeutic strategies and improving existing treatment modalities.

In comparison to alternative models, our ABCF3 Gene Knockout Cell Lines are characterized by high specificity, stability, and ease of use, facilitating more reliable and reproducible experimental outcomes. Furthermore, our cell lines are validated for functionality in various assays, including cellular proliferation and drug susceptibility studies, providing researchers with confidence in their experimental results.

For researchers and clinicians alike, ABCF3 Gene Knockout Cell Lines represent an essential resource that supports innovative research and enhances understanding of critical biological mechanisms. By investing in our product, users gain access to a powerful tool backed by our company’s extensive expertise in genetic engineering and cell line development, ensuring they are equipped with cutting-edge resources vital for advancing their research objectives.

Please note that all services are for research use only. Not intended for any clinical use.

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