Gene: ABCB10
Official Full Name: ATP binding cassette subfamily B member 10provided by HGNC
Gene Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The function of this mitochondrial protein is unknown. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29292 | ABCB10 Knockout cell line (HeLa) | Human | ABCB10 | 1:3~1:6 | Negative | Online Inquiry |
KO29293 | ABCB10 Knockout cell line (HCT 116) | Human | ABCB10 | 1:2~1:4 | Negative | Online Inquiry |
KO29294 | ABCB10 Knockout cell line (HEK293) | Human | ABCB10 | 1:3~1:6 | Negative | Online Inquiry |
KO29295 | ABCB10 Knockout cell line (A549) | Human | ABCB10 | 1:3~1:4 | Negative | Online Inquiry |
ABCB10 Gene Knockout Cell Lines represent a groundbreaking tool in the field of molecular biology, specifically designed to facilitate the study of the ATP-binding cassette (ABC) transporter family. The ABCB10 gene encodes a protein that plays a critical role in cellular export of various substrates, including vital metabolites and drugs. These knockout cell lines are generated via CRISPR/Cas9 gene-editing technology, effectively disrupting the ABCB10 gene to provide researchers with a functional model for exploring the gene's biological roles, interactions, and contributions to disease mechanisms.
The primary function of ABCB10 is to regulate the transport of molecules across the cell membrane, which is crucial in maintaining cellular homeostasis. By knocking out this gene, researchers can investigate the resultant phenotypic changes, such as altered metabolic pathways and sensitivity to certain drugs, thereby elucidating the gene's role in both normal physiology and pathophysiological conditions, such as cancer and genetic disorders. The understanding gained through such studies holds significant implications for therapeutic strategies and drug development.
In clinical and research settings, ABCB10 knockout cell lines provide invaluable insights into drug resistance mechanisms and the biology of various diseases. They serve as powerful models for assessing the efficacy of new pharmacological agents and understanding transport-related diseases, paving the way for novel therapeutic interventions.
One of the standout advantages of utilizing ABCB10 knockout cell lines from our company lies in their high specificity and reproducibility, attributes that enhance the reliability of experimental outcomes. Unlike other models, our cell lines are rigorously validated, assuring researchers of their fidelity and applicability in diverse experimental contexts.
By investing in ABCB10 gene knockout cell lines, researchers and clinicians gain access to a robust platform that accelerates discoveries in pharmacology, genetics, and cellular biology. Our commitment to advancing scientific knowledge is reflected in our expertise and premium product offerings, ensuring that our clients can rely on high-quality solutions tailored to their research needs.
Please note that all services are for research use only. Not intended for any clinical use.
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