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AAR2 Knockout Cell Lines

Gene: AAR2

Official Full Name: AAR2 splicing factorprovided by HGNC

Gene Summary: This gene encodes the homolog of the yeast A1-alpha2 repressin protein that is involved in mRNA splicing. Alternately spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28527 AAR2 Knockout cell line (HeLa) Human AAR2 1:3~1:6 Negative Online Inquiry
KO28528 AAR2 Knockout cell line (HCT 116) Human AAR2 1:2~1:4 Negative Online Inquiry
KO28529 AAR2 Knockout cell line (HEK293) Human AAR2 1:3~1:6 Negative Online Inquiry
KO28530 AAR2 Knockout cell line (A549) Human AAR2 1:3~1:4 Negative Online Inquiry

Background

AAR2 Gene Knockout Cell Lines represent a state-of-the-art tool in the study of gene function and cellular pathways. These cell lines are specifically engineered to have the AAR2 gene disrupted, providing researchers with a unique opportunity to examine the effects of AAR2 deficiency on cellular processes. Utilizing CRISPR/Cas9 technology, the knockout mechanism ensures high specificity and efficiency in targeting the gene, enabling precise analysis of its physiological roles.

The primary function of AAR2 within cells is its involvement in the regulation of RNA splicing and gene expression, crucial for maintaining cellular homeostasis and proper gene turnover. By utilizing AAR2 Gene Knockout Cell Lines, researchers can elucidate the downstream effects of AAR2 in various signaling pathways, investigate alternative splicing mechanisms, and assess the impact of AAR2 loss on cell proliferation and apoptosis.

In terms of scientific significance, these cell lines have extensive applications in both basic research and clinical studies. They serve as valuable models to study genetic disorders related to splicing mutations, cancer biology involving cellular transformations, and therapeutic targeting strategies. The ability to observe phenotypic changes directly related to the knockout of AAR2 offers translational insights that can pave the way for developing novel diagnostic and therapeutic approaches.

A key advantage of our AAR2 Gene Knockout Cell Lines lies in their robustness and ease of use compared to traditional knockout methods, which may involve complex procedures and lower efficiency. Our cell lines are validated and ready for immediate experimental application, eliminating the time and resources typically invested in generating knockout models from scratch. This practicality not only accelerates research timelines but also provides researchers and clinicians with reliable data that can support further studies on therapeutic interventions.

Furthermore, our company specializes in providing high-quality biological products equipped with cutting-edge molecular tools. Our team of experts is dedicated to ensuring our products meet the rigorous demands of the scientific community, making the AAR2 Gene Knockout Cell Lines an indispensable resource for advancing your research objectives.

Please note that all services are for research use only. Not intended for any clinical use.

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