E. Hypothetical cholesterol biosynthesis pathway in Salina

Nat. Commun— De novo biosynthesis of cholesterol in bacteria

Sterols have various important physiological functions, and their biosynthesis and function have been fully studied in eukaryotes. However, the synthesis and function of bacterial sterols are relatively poorly explored. There are several bacteria known to produce sterols from scratch, including aerobic methane oxidizing bacteria, floating mold, and various slime bacteria. Unlike eukaryotes, these bacteria mainly…

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Saccharomyces cerevisiae efficiently produces the spice raspberry ketone on a chassis, with the highest reported yield currently

Raspberry ketone is the main aromatic compound of red raspberry, which has wide applications in cosmetics, food, and medicine. In recent years, raspberry ketone has attracted wide attention as a essence and dietary supplement.   However, the natural abundance of raspberry ketone is low, with only 1-4 milligrams extracted from 1 kilogram of raspberry, making…

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